Document Detail


Old King coal - molecular mechanisms underlying an ancient treatment for atopic eczema.
MedLine Citation:
PMID:  23348733     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Traditional remedies for common disorders have been known for centuries, but insight into their mechanism of action is often limited. In this issue of the JCI, Joost Schalkwijk's research group at the Radboud University Nijmegen Medical Centre in The Netherlands advances our understanding of why topical coal tar is an effective treatment for atopic dermatitis (AD), both rationalizing the use of this traditional medicine, and providing the scientific basis for new therapeutic approaches.
Authors:
W H Irwin McLean; Alan D Irvine
Related Documents :
24136683 - The use of pde-5 inhibitors in the treatment of lower urinary tract symptoms due to ben...
22229953 - Risk assessment of engineered nanomaterials: a review of available data and approaches ...
16317203 - Tobacco industry influence on science and scientists in germany.
Publication Detail:
Type:  Comment; Journal Article; Research Support, Non-U.S. Gov't     Date:  2013-01-25
Journal Detail:
Title:  The Journal of clinical investigation     Volume:  123     ISSN:  1558-8238     ISO Abbreviation:  J. Clin. Invest.     Publication Date:  2013 Feb 
Date Detail:
Created Date:  2013-04-19     Completed Date:  2013-05-13     Revised Date:  2014-02-24    
Medline Journal Info:
Nlm Unique ID:  7802877     Medline TA:  J Clin Invest     Country:  United States    
Other Details:
Languages:  eng     Pagination:  551-3     Citation Subset:  AIM; IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Coal Tar / administration & dosage*
Dermatitis, Atopic / drug therapy*,  physiopathology*
Humans
Receptors, Aryl Hydrocarbon / drug effects*,  physiology*
Grant Support
ID/Acronym/Agency:
090066/B/09/Z//Wellcome Trust; 092530/Z/10/Z//Wellcome Trust; 098439//Wellcome Trust; 098439/Z/12/Z//Wellcome Trust; G0802780//Medical Research Council
Chemical
Reg. No./Substance:
0/Receptors, Aryl Hydrocarbon; 8007-45-2/Coal Tar
Comments/Corrections
Comment On:
J Clin Invest. 2013 Feb 1;123(2):917-27   [PMID:  23348739 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  iRHOM2 takes control of rheumatoid arthritis.
Next Document:  Cancer therapy combination: green tea and a phosphodiesterase 5 inhibitor?