Document Detail

Old King coal - molecular mechanisms underlying an ancient treatment for atopic eczema.
MedLine Citation:
PMID:  23348733     Owner:  NLM     Status:  MEDLINE    
Traditional remedies for common disorders have been known for centuries, but insight into their mechanism of action is often limited. In this issue of the JCI, Joost Schalkwijk's research group at the Radboud University Nijmegen Medical Centre in The Netherlands advances our understanding of why topical coal tar is an effective treatment for atopic dermatitis (AD), both rationalizing the use of this traditional medicine, and providing the scientific basis for new therapeutic approaches.
W H Irwin McLean; Alan D Irvine
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Publication Detail:
Type:  Comment; Journal Article; Research Support, Non-U.S. Gov't     Date:  2013-01-25
Journal Detail:
Title:  The Journal of clinical investigation     Volume:  123     ISSN:  1558-8238     ISO Abbreviation:  J. Clin. Invest.     Publication Date:  2013 Feb 
Date Detail:
Created Date:  2013-04-19     Completed Date:  2013-05-13     Revised Date:  2014-02-24    
Medline Journal Info:
Nlm Unique ID:  7802877     Medline TA:  J Clin Invest     Country:  United States    
Other Details:
Languages:  eng     Pagination:  551-3     Citation Subset:  AIM; IM    
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MeSH Terms
Coal Tar / administration & dosage*
Dermatitis, Atopic / drug therapy*,  physiopathology*
Receptors, Aryl Hydrocarbon / drug effects*,  physiology*
Grant Support
090066/B/09/Z//Wellcome Trust; 092530/Z/10/Z//Wellcome Trust; 098439//Wellcome Trust; 098439/Z/12/Z//Wellcome Trust; G0802780//Medical Research Council
Reg. No./Substance:
0/Receptors, Aryl Hydrocarbon; 8007-45-2/Coal Tar
Comment On:
J Clin Invest. 2013 Feb 1;123(2):917-27   [PMID:  23348739 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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