Document Detail

Olanzapine-induced agranulocytosis: a case report and review of the literature.
MedLine Citation:
PMID:  11817522     Owner:  NLM     Status:  MEDLINE    
The novel antipsychotic olanzapine has structural and pharmacological properties similar to clozapine. Until recently, no haematological toxicity has been reported with olanzapine use and it was expected to be a safer alternative. The authors report a case of agranulocytosis induced by olanzapine and reviewed the 11 cases reported in the literature.
Carles Tolosa-Vilella; Ada Ruiz-Ripoll; Begoña Mari-Alfonso; Elsa Naval-Sendra
Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  Progress in neuro-psychopharmacology & biological psychiatry     Volume:  26     ISSN:  0278-5846     ISO Abbreviation:  Prog. Neuropsychopharmacol. Biol. Psychiatry     Publication Date:  2002 Feb 
Date Detail:
Created Date:  2002-01-30     Completed Date:  2002-07-22     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  8211617     Medline TA:  Prog Neuropsychopharmacol Biol Psychiatry     Country:  England    
Other Details:
Languages:  eng     Pagination:  411-4     Citation Subset:  IM    
Department of Internal Medicine, Consorci Sanitari Parc Taulí, Sabadell, Barcelona, Spain.
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MeSH Terms
Agranulocytosis / blood,  chemically induced*,  physiopathology
Antipsychotic Agents / adverse effects*
Middle Aged
Pirenzepine / adverse effects*,  analogs & derivatives
Reg. No./Substance:
0/Antipsychotic Agents; 12794-10-4/Benzodiazepines; 132539-06-1/olanzapine; 28797-61-7/Pirenzepine

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