| Olanzapine and food craving: a case control study. | |
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MedLine Citation:
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PMID: 23169487 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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BACKGROUND: Antipsychotic-induced weight gain is a problematic side effect. The mechanism is still not fully understood. Carbohydrate (and possibly other food) cravings have been suggested in literature, but not been systematically investigated. OBJECTIVES: To investigate the hypothesis that food cravings, especially for carbohydrate, are responsible for olanzapine-induced weight gain. METHOD: A case control design was used to measure general and specific food cravings using Food Craving Inventory (White et al., 2002) in three groups: patients with a diagnosis of schizophrenia taking olanzapine (Number = 20) or typical antipsychotics (Number = 20) and in a healthy control group (Number = 20). RESULTS: No statistically significant differences were found between the three groups in the craving scores. There was a trend in the typical group to show more cravings than other groups. CONCLUSION: Our study failed to prove the hypothesis that carbohydrate craving is responsible for olanzapine-induced weight gain. This conclusion is limited by the small number of the subjects included. Copyright © 2012 John Wiley & Sons, Ltd. |
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Authors:
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Mohammed J Abbas; Peter F Liddle |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-11-21 |
Journal Detail:
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Title: Human psychopharmacology Volume: - ISSN: 1099-1077 ISO Abbreviation: Hum Psychopharmacol Publication Date: 2012 Nov |
Date Detail:
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Created Date: 2012-11-21 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8702539 Medline TA: Hum Psychopharmacol Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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Copyright © 2012 John Wiley & Sons, Ltd. |
Affiliation:
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Bradgate Mental Health Unit, Leicester, UK. mohdgum@hotmail.com. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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