Document Detail

Office-based cryoablation of breast fibroadenomas with long-term follow-up.
MedLine Citation:
PMID:  16174156     Owner:  NLM     Status:  MEDLINE    
Approximately 10% of women will experience a breast fibroadenoma in their lifetime. Cryoablation is a new treatment that combines the better attributes of the current standards: surveillance and surgery. It is a minimally invasive office-based procedure that is administered without the use of general anesthesia, involving minimal patient discomfort and little to no scarring. This work aimed to establish the long-term (2-3 years) efficacy, safety, and satisfaction of the procedure, as well as the impact of cryoablation on mammogram and ultrasound images. Thirty-seven treated fibroadenomas were available for assessment with an average follow-up period of 2.6 years. Of the original 84% that were palpable prior to treatment, only 16% remained palpable to the patient as of this writing. Of those fibroadenomas that were initially < or = 2.0 cm in size, only 6% remained palpable. A median volume reduction of 99% was observed with ultrasound. Ninety-seven percent of patients and 100% of physicians were satisfied with the long-term treatment results. Mammograms and ultrasounds showed cryoablation produced no artifact that would adversely affect interpretation. Cryoablation for breast fibroadenomas has previously been reported as safe and effective both acutely and at the 1-year follow-up mark, and thus has been implemented as a treatment option. At long-term follow-up, cryoablation as a primary therapy for breast fibroadenomas demonstrates progressive resolution of the treated area, durable safety, and excellent patient and physician satisfaction. The treatment is performed in an office setting rather than an operating room, resulting in a cost-effective and patient-friendly procedure. Cryoablation should be considered a preferred option for those patients desiring definitive therapy for their fibroadenomas without surgical intervention.
Cary S Kaufman; Peter J Littrup; Laurie A Freeman-Gibb; J Stanley Smith; Darius Francescatti; Rache Simmons; Lewis H Stocks; Lisa Bailey; Jay K Harness; Barbara A Bachman; C Alan Henry
Related Documents :
15474426 - Partial breast irradiation in breast conserving therapy by way of intersitial brachythe...
15761426 - Intralesional 5-fluorouracil in the treatment of keloids: an open clinical and histopat...
15114126 - Evaluation of abdominal wall strength after tram flap surgery.
23925516 - Sulfonylcarbamate as a versatile and unique hydroxy-protecting group: a protecting grou...
18775076 - Radiographic outcome of surgical treatment of adolescent idiopathic scoliosis in males ...
25356146 - Subclinical hypothyroidism is a risk factor for delayed clinical complete response in p...
Publication Detail:
Type:  Clinical Trial; Comparative Study; Journal Article    
Journal Detail:
Title:  The breast journal     Volume:  11     ISSN:  1075-122X     ISO Abbreviation:  Breast J     Publication Date:    2005 Sep-Oct
Date Detail:
Created Date:  2005-09-21     Completed Date:  2005-11-15     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9505539     Medline TA:  Breast J     Country:  United States    
Other Details:
Languages:  eng     Pagination:  344-50     Citation Subset:  IM    
University of Washington and the Bellingham Breast Center, Bellingham, Washington 98225, USA.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Ambulatory Surgical Procedures
Breast Neoplasms / diagnosis*,  surgery*
Cryosurgery / adverse effects,  methods*
Fibroadenoma / diagnosis*,  surgery*
Follow-Up Studies
Mammography / methods
Middle Aged
Neoplasm Staging
Patient Satisfaction
Prospective Studies
Risk Assessment
Time Factors
Treatment Outcome
Ultrasonography, Mammary / methods

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Primary tumor characteristics predict sentinel lymph node macrometastasis in breast cancer.
Next Document:  Primary gastrointestinal lymphomas: a radiological-pathological review. Part 1: Stomach, oesophagus ...