| Office management of peripheral arterial disease. | |
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MedLine Citation:
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PMID: 20800143 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Patients with peripheral arterial disease are at increased risk for all-cause mortality, cardiovascular mortality, and mortality from coronary artery disease. Smoking should be stopped, and hypertension, diabetes mellitus, and dyslipidemia should be treated. Statins reduce the incidence of intermittent claudication and increase exercise duration until the onset of intermittent claudication in patients with peripheral arterial disease and hypercholesterolemia. Antiplatelet drugs, such as aspirin or clopidogrel, angiotensin-converting enzyme inhibitors, and statins, should be given to all patients with peripheral arterial disease. Beta-blockers should be given if coronary artery disease is present. Exercise rehabilitation programs and cilostazol improve exercise time until the onset of intermittent claudication. Indications for lower-extremity angioplasty, preferably with stenting, or bypass surgery are incapacitating claudication interfering with work or lifestyle in patients; limb salvage in patients with limb-threatening ischemia as manifested by rest pain, nonhealing ulcers, infection, or gangrene; and vasculogenic impotence. |
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Authors:
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Wilbert S Aronow |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The American journal of medicine Volume: 123 ISSN: 1555-7162 ISO Abbreviation: Am. J. Med. Publication Date: 2010 Sep |
Date Detail:
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Created Date: 2010-08-30 Completed Date: 2010-09-13 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0267200 Medline TA: Am J Med Country: United States |
Other Details:
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Languages: eng Pagination: 790-2 Citation Subset: AIM; IM |
Affiliation:
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Department of Medicine, New York Medical College, Valhalla, NY, USA. wsaronow@aol.com |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adrenergic beta-Antagonists
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therapeutic use Ambulatory Care* / methods Angioplasty Angiotensin-Converting Enzyme Inhibitors / therapeutic use Coronary Artery Disease / complications, drug therapy Diabetes Complications / drug therapy Dyslipidemias / complications, drug therapy Exercise Tolerance Humans Hydroxymethylglutaryl-CoA Reductase Inhibitors / therapeutic use Hypertension / complications, drug therapy Intermittent Claudication / etiology, therapy Ischemia / therapy Lower Extremity / blood supply* Office Visits Peripheral Vascular Diseases / diagnosis*, drug therapy*, etiology Platelet Aggregation Inhibitors / therapeutic use Risk Factors Risk Reduction Behavior Smoking / adverse effects Smoking Cessation Stents |
| Chemical | |
Reg. No./Substance:
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0/Adrenergic beta-Antagonists; 0/Angiotensin-Converting Enzyme Inhibitors; 0/Hydroxymethylglutaryl-CoA Reductase Inhibitors; 0/Platelet Aggregation Inhibitors |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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