Document Detail

Off-pump coronary artery bypass grafting decreases risk-adjusted mortality and morbidity.
MedLine Citation:
PMID:  11603449     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: The purpose of this study was to determine whether coronary artery bypass grafting without cardiopulmonary bypass (off-pump CABG) decreases risk-adjusted operative death and major complications after coronary artery bypass grafting in selected patients. METHODS: Using The Society of Thoracic Surgeons (STS) National Adult Cardiac Surgery Database, procedural outcomes were compared for conventional and off-pump CABG procedures from January 1, 1998, through December 31, 1999. Mortality and major complications were examined, both as unadjusted rates and after adjusting for known base line patient risk factors. RESULTS: A total of 126 experienced centers performed 118,140 total CABG procedures. The number of off-pump CABG cases was 11,717 cases (9.9% of total cases). The use of an off-pump procedure was associated with a decrease in risk-adjusted operative mortality from 2.9% with conventional CABG to 2.3% in the off-pump group (p < 0.001). The use of an off-pump procedure decreased the risk-adjusted major complication rate from 14.15% with conventional CABG to 10.62% in the off-pump group (p < 0.0001). Patients receiving off-pump procedures were less likely to die (adjusted odds ratio 0.81, 95% CI 0.70 to 0.91) and less likely to have major complications (adjusted odds ratio 0.77, 95% CI 0.72 to 0.82). CONCLUSIONS: Off-pump CABG is associated with decreased mortality and morbidity after coronary artery bypass grafting. Off-pump CABG may prove superior to conventional CABG in appropriately selected patients.
J C Cleveland; A L Shroyer; A Y Chen; E Peterson; F L Grover
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Publication Detail:
Type:  Comparative Study; Evaluation Studies; Journal Article; Multicenter Study    
Journal Detail:
Title:  The Annals of thoracic surgery     Volume:  72     ISSN:  0003-4975     ISO Abbreviation:  Ann. Thorac. Surg.     Publication Date:  2001 Oct 
Date Detail:
Created Date:  2001-10-17     Completed Date:  2001-12-04     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  15030100R     Medline TA:  Ann Thorac Surg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1282-8; discussion 1288-9     Citation Subset:  AIM; IM    
Division of Cardiothoracic Surgery, University of Colorado Health Sciences Center, Denver 80262, USA.
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MeSH Terms
Cardiopulmonary Bypass*
Coronary Artery Bypass*
Coronary Disease / mortality,  surgery*
Follow-Up Studies
Hospital Mortality
Middle Aged
Postoperative Complications / mortality*
Survival Rate

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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