Document Detail

Oesophageal intraluminal impedance can identify subtle bolus transit abnormalities in patients with mild oesophagitis.
MedLine Citation:
PMID:  15716653     Owner:  NLM     Status:  MEDLINE    
In a subgroup of patients with non-erosive gastroesophageal reflux disease (GORD) or mild oesophagitis, acid clearance is prolonged in spite of favourable gravity and normal or minimally impaired oesophageal peristalsis. Dysphagia is rare in this group but might also be present or develop after anti-reflux surgery. The causal relationship between prolonged clearance or dysphagia and oesophageal body dysmotility in these patients is not completely clear. New techniques are now available to assess oesophageal motility and transit and might help to detect more subtle defects underlying functional impairment in patients with GORD. Combined video-fluoroscopy and intraluminal impedance indicate an excellent correlation between both methods in detecting oesophageal bolus transit. Combined intraluminal impedance and manometry has the capability to evaluate oesophageal contractions and bolus transit without the use of radiation. Subtle bolus transit abnormalities were identified in a small proportion of patients with mild oesophagits and normal oesophageal peristalsis. Outcome data are needed to evaluate the prognostic value of combined manometry-impedance in patients with GORD undergoing anti-reflux surgery.
Daniel Sifrim; Radu Tutuian
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Publication Detail:
Type:  Comment; Journal Article; Review    
Journal Detail:
Title:  European journal of gastroenterology & hepatology     Volume:  17     ISSN:  0954-691X     ISO Abbreviation:  Eur J Gastroenterol Hepatol     Publication Date:  2005 Mar 
Date Detail:
Created Date:  2005-02-17     Completed Date:  2005-06-06     Revised Date:  2009-10-16    
Medline Journal Info:
Nlm Unique ID:  9000874     Medline TA:  Eur J Gastroenterol Hepatol     Country:  England    
Other Details:
Languages:  eng     Pagination:  303-5     Citation Subset:  IM    
Centre for Gastroenterological Research, Catholic University of Leuven, O & N Gasthiusberg, Leuven, Belgium.
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MeSH Terms
Electric Impedance / diagnostic use
Esophagitis, Peptic / physiopathology*
Esophagus / physiopathology
Fluoroscopy / methods
Gastroesophageal Reflux / physiopathology*
Manometry / methods
Peristalsis / physiology
Comment On:
Eur J Gastroenterol Hepatol. 2005 Mar;17(3):323-32   [PMID:  15716657 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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