| Odor structure-activity relationships compared in human and nonhuman primates. | |
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MedLine Citation:
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PMID: 10571482 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The ability of 4 squirrel monkeys to distinguish between members of 3 homologous series of substances (aliphatic alcohols, aldehydes, and ketones) was investigated, and their performance was compared with that of a group of 10 human participants. With all 3 substance classes, and in both species, a significant negative correlation was found between discrimination performance and structural similarity of odorants in terms of differences in carbon chain length. These findings suggest carbon chain length of aliphatic odorants to be one of presumably several determinants of the interaction between stimulus molecule and olfactory receptor and support the assumption that human and nonhuman primates may share common mechanisms of odor quality perception. |
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Authors:
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M Laska; S Trolp; P Teubner |
Publication Detail:
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Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Behavioral neuroscience Volume: 113 ISSN: 0735-7044 ISO Abbreviation: Behav. Neurosci. Publication Date: 1999 Oct |
Date Detail:
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Created Date: 1999-12-02 Completed Date: 1999-12-02 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8302411 Medline TA: Behav Neurosci Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 998-1007 Citation Subset: IM |
Affiliation:
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Department of Medical Psychology, University of Munich Medical School, Germany. Laska@imp.med.uni-muenchen.de |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Alcohols / analysis*, chemistry Aldehydes / analysis*, chemistry Analysis of Variance Animals Discrimination Learning / physiology* Female Humans Ketones / analysis*, chemistry Male Odors / analysis* Receptors, Odorant / physiology Saimiri Smell / physiology* Structure-Activity Relationship |
| Chemical | |
Reg. No./Substance:
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0/Alcohols; 0/Aldehydes; 0/Ketones; 0/Receptors, Odorant |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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