| Odontogenic myxoma in an 8-year-old Labrador Retriever dog. | |
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MedLine Citation:
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PMID: 21217053 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Odontogenic myxoma (OM) was diagnosed in an 8-year-old Labrador Retriever dog with an ulcerohemorrhagic mass located on the caudal area of the right maxillary gingiva. The neoplasm was characterized by a low mitotic index and moderate numbers of spindle, stellate, and round cells that were sparsely distributed in an alcian blue reactive myxomatous matrix. Individual neoplastic cells were characterized by small amounts of faintly eosinophilic staining cytoplasm, prominent nucleoli, and stippled amphophilic staining chromatin that was immunoreactive for vimentin but negative for cytokeratin and actin. To the authors' knowledge, this is the first reported case of canine OM from North America, and it shares histomorphologic and histochemical features with 3 other cases reported in dogs elsewhere. Whereas, a literature review suggests untreated canine OM is insidious and locally aggressive, the prognosis in the present dog remains unknown. These findings support previous recommendations for inclusion of canine OM on the World Health Organization list of odontogenic tumors. |
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Authors:
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Robert Barigye; Jessie Schultz; Teresa K Newell; Neil W Dyer |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc Volume: 23 ISSN: 1943-4936 ISO Abbreviation: J. Vet. Diagn. Invest. Publication Date: 2011 Jan |
Date Detail:
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Created Date: 2011-01-10 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9011490 Medline TA: J Vet Diagn Invest Country: United States |
Other Details:
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Languages: eng Pagination: 167-71 Citation Subset: IM |
Affiliation:
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Department of Veterinary and Microbiological Sciences, Department of Veterinary Diagnostic Services, North Dakota State University, 1523 Centennial Boulevard, Fargo, ND 58108. Robert.Barigye@ndsu.edu. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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