Document Detail

Ocular surface disease: A case of vernal keratoconjunctivitis.
MedLine Citation:
PMID:  20971677     Owner:  NLM     Status:  In-Data-Review    
Vernal keratoconjunctivitis (VKC) is a recurrent, chronic allergic inflammation of the ocular surface associated with remodeling of the cornea and conjunctiva, with a potential to adversely affect the patient's vision and quality of life. It affects mainly children and young adults. The purpose of this interventional case report is to present a typical case of limbal VKC, which was unresponsive to antiallergic treatment alone. A 5-year-old boy, who was previously unsuccessful with conventional anti-allergic therapy alone, presented with clinicopathological features pathognomonic of limbal VKC. The patient was successfully managed with a combination of palliative, anti-allergic and anti-inflammatory therapy. Prophylaxis with an anti-allergic pharmaceutical agent was initiated for long term use to prevent the release of allergic mediators. This case highlights the importance of prescribing the most appropriate pharmaceutical medication for VKC since conjunctival fibroproliferative lesions are often resistant to anti-allergy therapy. Allergic inflammatory mediators are responsible for the fibroproliferative changes of the conjunctiva and corneal lesions in VKC. Thus, it is crucial to prescribe the most appropriate pharmaceutical medication that will prevent the release of allergic inflammatory mediators, control the allergic inflammatory cascade and prevent ocular surface damage. The fine points of this case are presented with a review of applicable literature.
Degaulle I Chigbu; Shanthy Sandrasekaramudaly-Brown
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Publication Detail:
Type:  Journal Article     Date:  2010-10-25
Journal Detail:
Title:  Contact lens & anterior eye : the journal of the British Contact Lens Association     Volume:  34     ISSN:  1476-5411     ISO Abbreviation:  Cont Lens Anterior Eye     Publication Date:  2011 Feb 
Date Detail:
Created Date:  2011-01-18     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9712714     Medline TA:  Cont Lens Anterior Eye     Country:  England    
Other Details:
Languages:  eng     Pagination:  39-44     Citation Subset:  IM    
Copyright Information:
Copyright © 2010 British Contact Lens Association. Published by Elsevier Ltd. All rights reserved.
Pennsylvania College of Optometry at Salus University, 8360 Old York Road, Elkins Park, PA 19027, USA.
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