Document Detail

Ocular masquerade syndrome in lymphoid blast crisis of chronic myeloid leukemia.
MedLine Citation:
PMID:  8750639     Owner:  NLM     Status:  MEDLINE    
A 56-year-old woman presented with CML in lymphoid blast crisis. Complete remission with no suggestion of CML was achieved with chemotherapy. Twenty-six months later, an isolated ocular anterior chamber relapse of acute leukemia presenting as uveitis (ocular masquerade syndrome) was diagnosed and treated with radiotherapy. Ten months later, a second ocular relapse in the same location was diagnosed and treated with radiotherapy. Two months later, a systemic relapse into second chronic phase was diagnosed and is currently being treated with alpha interferon. Only one previous case of leukemic hypopyon in CML has been reported. This is also the first case of isolated ocular blast crisis relapse in CML to be described.
J H Lipton; H D McGowan; D G Payne
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Leukemia & lymphoma     Volume:  20     ISSN:  1042-8194     ISO Abbreviation:  Leuk. Lymphoma     Publication Date:  1995 Dec 
Date Detail:
Created Date:  1996-10-17     Completed Date:  1996-10-17     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  9007422     Medline TA:  Leuk Lymphoma     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  161-3     Citation Subset:  IM    
Department of Medicine, University of Toronto, Ontario, Canada.
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MeSH Terms
Blast Crisis*
Cobalt Radioisotopes / therapeutic use
Eye Neoplasms / pathology*,  radiotherapy,  secondary*,  therapy
Interferon-alpha / therapeutic use
Leukemia, Myelogenous, Chronic, BCR-ABL Positive / drug therapy,  pathology*,  therapy
Middle Aged
Uveitis / etiology*
Reg. No./Substance:
0/Cobalt Radioisotopes; 0/Interferon-alpha

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