| OCULAR MANIFESTATIONS OF TAKAYASU ARTERITIS-A CROSS-SECTIONAL STUDY. | |
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MedLine Citation:
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PMID: 21317836 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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PURPOSE:: To detail the spectrum of eye manifestations in Takayasu arteritis and factors predisposing to its development. METHODS:: In this cross-sectional study, 61 patients with proven Takayasu arteritis who were identified during a 16-month period were evaluated for disease- and treatment-related eye manifestations. A fundus fluorescein angiography examination was performed where indicated and with the patients consent. RESULTS:: The mean (±standard deviation) duration of illness before ophthalmic evaluation was 55 ± 69 months. Decreased vision was the most common ocular symptom (30%). Thirty-five patients underwent fundus fluorescein angiography examination. Takayasu retinopathy was seen in 9 (15%), ocular ischemic syndrome in 4 (7%), and hypertensive retinopathy in 10 (16%) patients. The most common treatment-related ocular complication was steroid-induced cataract (23%). Other manifestations included iris neovascularization (n = 3), anterior ischemic optic neuropathy (n = 2), steroid-induced glaucoma (n = 1), neovascular glaucoma (n = 1), and uveitis (n = 1). Those manifesting Takayasu retinopathy and ocular ischemic syndrome had significantly (P < 0.05) lower blood pressure in both upper limbs compared with patients not manifesting ischemic retinopathy. A significant (P < 0.03) proportion of patients with Takayasu retinopathy and ocular ischemic syndrome had a nonrecordable right upper limb blood pressure. CONCLUSION:: Disease- and treatment-related ocular complications are not infrequent in Takayasu arteritis. Arteritis involving the aortic arch and its branches favors the development of ischemic ocular complications. |
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Authors:
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Jayanthi Peter; Sarada David; Debashish Danda; John Victor Peter; Saban Horo; George Joseph |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-2-11 |
Journal Detail:
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Title: Retina (Philadelphia, Pa.) Volume: - ISSN: 1539-2864 ISO Abbreviation: - Publication Date: 2011 Feb |
Date Detail:
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Created Date: 2011-2-14 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8309919 Medline TA: Retina Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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From the *Schell Eye Hospital, †Department of Rheumatology & Immunology, ‡Department of Medicine, and §Department of Cardiology, Christian Medical College & Hospital, Vellore, India. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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