Document Detail

Ocular manifestations in children and adolescents with Lyme arthritis.
MedLine Citation:
PMID:  10502576     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Lyme arthritis is the most frequent late manifestation of Lyme borreliosis and has been associated with ocular inflammation. METHODS: A group of 153 children and adolescents with arthritis, 84 of whom had Lyme arthritis and 69 other causes of arthritis, were followed prospectively for 22-73 (median 44) months in the course of a national study. RESULTS: Three of 84 patients with Lyme arthritis had ocular inflammation (4%), including keratitis, anterior uveitis, and uveitis intermedia. All three had symptoms of decreased visual acuity. Whereas anterior uveitis disappeared without sequelae, a corneal scar and a permanent loss of visual acuity in the patients with keratitis and intermediate uveitis remained. Systematic examination of all patients revealed no further ocular involvement. Of 69 patients with other causes of arthritis who were followed in parallel as a control group, four of 15 patients with early onset pauciarticular juvenile rheumatoid arthritis had chronic anterior uveitis and two of 12 patients with juvenile spondyloarthropathy had acute anterior uveitis. CONCLUSIONS: Ocular involvement with keratitis, anterior uveitis, and intermediate uveitis may occur in children and adolescents with Lyme arthritis. Visual loss appears to be symptomatic, making regular ocular screening of such patients unnecessary.
H I Huppertz; D Münchmeier; W Lieb
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Publication Detail:
Type:  Journal Article; Multicenter Study    
Journal Detail:
Title:  The British journal of ophthalmology     Volume:  83     ISSN:  0007-1161     ISO Abbreviation:  Br J Ophthalmol     Publication Date:  1999 Oct 
Date Detail:
Created Date:  2000-01-11     Completed Date:  2000-01-11     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  0421041     Medline TA:  Br J Ophthalmol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  1149-52     Citation Subset:  IM    
Children's Hospital, University of Würzburg, Würzburg, Germany.
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MeSH Terms
Arthritis, Infectious / complications*
Child, Preschool
Eye Infections, Bacterial / complications*,  physiopathology
Follow-Up Studies
Keratitis / microbiology
Lyme Disease / complications*,  physiopathology
Prospective Studies
Uveitis, Anterior / microbiology
Uveitis, Intermediate / microbiology
Visual Acuity

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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