Document Detail

Ocular ischemia with hypotony after injection of hyaluronic acid gel.
MedLine Citation:
PMID:  22082564     Owner:  NLM     Status:  MEDLINE    
The authors experienced a case with ocular ischemia with hypotony following injection of a dermal filler for augmentation rhinoplasty. Immediately after injection, the patient demonstrated a permanent visual loss with typical fundus features of central retinal artery occlusion. Multiple crusted ulcerative patches around the nose and left periorbit developed, and the left eye became severely inflamed, ophthalmoplegic, and hypotonic. Signs of anterior and posterior segment ischemia were observed including severe cornea edema, iris atrophy, and chorioretinal swelling. The retrograde arterial embolization of hyaluronic acid gel from vascular branches of nasal tip to central retinal artery and long posterior ciliary artery was highly suspicious. After 6 months of follow up, skin lesions and eyeball movement became normalized, but progressive exudative and tractional retinal detachment was causing phthisis bulbi.
Young Jun Kim; Sung Soo Kim; Won Kyung Song; Sang Yeul Lee; Jin Sook Yoon
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Ophthalmic plastic and reconstructive surgery     Volume:  27     ISSN:  1537-2677     ISO Abbreviation:  Ophthal Plast Reconstr Surg     Publication Date:    2011 Nov-Dec
Date Detail:
Created Date:  2011-11-15     Completed Date:  2012-01-20     Revised Date:  2013-05-08    
Medline Journal Info:
Nlm Unique ID:  8508431     Medline TA:  Ophthal Plast Reconstr Surg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  e152-5     Citation Subset:  IM    
Department of Ophthalmology, Institute of Vision Research, Yonsei University College of Medicine, Seoul, Korea.
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MeSH Terms
Blindness / etiology
Eye / blood supply*
Hyaluronic Acid / adverse effects,  analogs & derivatives*
Intraocular Pressure / drug effects*
Ischemia / chemically induced*
Ocular Hypotension / chemically induced*
Ocular Motility Disorders / chemically induced
Papilledema / chemically induced
Retinal Artery Occlusion / chemically induced
Skin Aging / drug effects
Skin Ulcer / chemically induced
Reg. No./Substance:
0/Gels; 0/Restylane; 9004-61-9/Hyaluronic Acid

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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