Document Detail

Ocular ischemia in high myopia treated with intravenous prostaglandin e1.
MedLine Citation:
PMID:  25389853     Owner:  NLM     Status:  In-Data-Review    
BACKGROUND: High myopia is associated with a decreased ocular blood flow. In some cases this ocular ischemia may be the cause of severe visual loss.
METHODS: Three patients with high myopia and progressive loss of visual acuity had a diagnosis of ocular ischemia by color Doppler. Intravenous prostaglandin E1, a powerful vasodilator of the microcirculation, was used to treat the ocular ischemia in all 3 patients.
RESULTS: The visual acuity improved in all three cases with one patient improving from 20/100 to 20/30. The mean deficit of the visual fields in this patient improved from -19.08 to -9.52 after treatment. The treatment was repeated every 6 weeks to 8 weeks.
CONCLUSION: Patients with high myopia and progressive visual acuity loss should be evaluated for ocular ischemia. Intravenous prostaglandin E1 should be considered in those cases of ocular ischemia with visual loss. Unfortunately the effect does not last for more than 6 weeks to 8 weeks and needs to be repeated at this interval for extended periods.
Robert D Steigerwalt; M Rosaria Cesarone; Gianni Belcaro; Antonella Pascarella; Laura Rapagnetta; Mauro De Angelis; Marcella Nebbioso
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Retinal cases & brief reports     Volume:  3     ISSN:  1935-1089     ISO Abbreviation:  Retin Cases Brief Rep     Publication Date:  2009  
Date Detail:
Created Date:  2014-11-13     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101298744     Medline TA:  Retin Cases Brief Rep     Country:  United States    
Other Details:
Languages:  eng     Pagination:  379-82     Citation Subset:  -    
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