Document Detail


Ocular hemodynamic changes in patients with high-grade carotid occlusive disease and development of chronic ocular ischaemia. II. Clinical findings.
MedLine Citation:
PMID:  7543004     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Ocular changes due to chronic ischaemia are described in 45 patients with hemodynamically significant carotid occlusive disease. Regarding the ophthalmic artery flow before and after vasodilatory stimulus, the patients were divided into four different groups. Eyes with permanent anterograde ophthalmic artery flow had evidence of embolic features, but no signs of chronic hypoperfusion. In the group where anterograde ophthalmic artery flow changed to retrograde after 1 g intravenous acetazolamide, the patients had symptoms of critical ocular perfusion, but only subtle structural changes could be demonstrated. Chronic ocular ischaemic syndromes were found in the cases with retrograde ophthalmic artery flow, especially where bilateral severe carotid obstruction was present.
Authors:
E Kerty; N Eide; I Hørven
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Acta ophthalmologica Scandinavica     Volume:  73     ISSN:  1395-3907     ISO Abbreviation:  Acta Ophthalmol Scand     Publication Date:  1995 Feb 
Date Detail:
Created Date:  1995-09-07     Completed Date:  1995-09-07     Revised Date:  2008-03-17    
Medline Journal Info:
Nlm Unique ID:  9507578     Medline TA:  Acta Ophthalmol Scand     Country:  DENMARK    
Other Details:
Languages:  eng     Pagination:  72-6     Citation Subset:  IM    
Affiliation:
Department of Neurology, Rikshospitalet, University of Oslo, Norway.
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MeSH Terms
Descriptor/Qualifier:
Acetazolamide / administration & dosage
Aged
Aged, 80 and over
Blindness
Blood Flow Velocity
Carotid Artery, Internal / physiopathology
Carotid Stenosis / physiopathology*
Chronic Disease
Eye / blood supply*
Female
Fluorescein Angiography
Humans
Injections, Intravenous
Ischemia / physiopathology*
Male
Middle Aged
Neovascularization, Pathologic
Ophthalmic Artery / physiology*
Retinal Artery Occlusion
Retinal Vessels / physiology
Tonometry, Ocular
Ultrasonography, Doppler
Visual Acuity
Chemical
Reg. No./Substance:
59-66-5/Acetazolamide

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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