| Ocular findings in leprosy patients in Nepal in the era of multidrug therapy. | |
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MedLine Citation:
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PMID: 15126154 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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PURPOSE: Detailed ophthalmic evaluation was performed to determine the prevalence of ocular complications among leprosy patients on multidrug therapy and those released from multidrug treatment. DESIGN: Observational case series. METHODS: Leprosy patients at Tribhuvan University Teaching Hospital from April 1, 2001, through September 30, 2002, underwent detailed ophthalmic evaluation including slit-lamp biomicroscopy, dilated funduscopy, and applanation tonometry. RESULTS: We evaluated 58 leprosy patients. A majority (72%) was receiving treatment for multibacillary leprosy; 14% belonged to posttreatment multibacillary and paucibacillary groups. Ocular involvement was found in 57% of patients. In the multibacillary group, 55% had ocular involvement, which was more than double that found in the paucibacillary group (25%), although this finding was not statistically significant (P =.187). Among patients with ocular complications, 48% had visual disability and another 45% had threatened vision; 9% met World Health Organization guidelines for blindness. Uveitis and its complications were the predominant causes of visual disability (88%). CONCLUSION: Ocular complications and visual disability are high among leprosy patients in Nepal even after completing multidrug therapy. |
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Authors:
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Bhagavat P Nepal; Ujjowala D Shrestha |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: American journal of ophthalmology Volume: 137 ISSN: 0002-9394 ISO Abbreviation: Am. J. Ophthalmol. Publication Date: 2004 May |
Date Detail:
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Created Date: 2004-05-05 Completed Date: 2004-06-03 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0370500 Medline TA: Am J Ophthalmol Country: United States |
Other Details:
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Languages: eng Pagination: 888-92 Citation Subset: AIM; IM |
Affiliation:
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BP Koirala Lions Center for Ophthalmic Studies, PO Box 8750, Maharajgunj, Kathmandu, Nepal. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Drug Therapy, Combination Eye Diseases / drug therapy, epidemiology*, etiology Female Humans Leprostatic Agents / therapeutic use* Leprosy / complications, drug therapy*, epidemiology* Male Middle Aged Nepal / epidemiology Prevalence |
| Chemical | |
Reg. No./Substance:
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0/Leprostatic Agents |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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