Document Detail

Ocular findings in leprosy patients in Nepal in the era of multidrug therapy.
MedLine Citation:
PMID:  15126154     Owner:  NLM     Status:  MEDLINE    
PURPOSE: Detailed ophthalmic evaluation was performed to determine the prevalence of ocular complications among leprosy patients on multidrug therapy and those released from multidrug treatment. DESIGN: Observational case series. METHODS: Leprosy patients at Tribhuvan University Teaching Hospital from April 1, 2001, through September 30, 2002, underwent detailed ophthalmic evaluation including slit-lamp biomicroscopy, dilated funduscopy, and applanation tonometry. RESULTS: We evaluated 58 leprosy patients. A majority (72%) was receiving treatment for multibacillary leprosy; 14% belonged to posttreatment multibacillary and paucibacillary groups. Ocular involvement was found in 57% of patients. In the multibacillary group, 55% had ocular involvement, which was more than double that found in the paucibacillary group (25%), although this finding was not statistically significant (P =.187). Among patients with ocular complications, 48% had visual disability and another 45% had threatened vision; 9% met World Health Organization guidelines for blindness. Uveitis and its complications were the predominant causes of visual disability (88%). CONCLUSION: Ocular complications and visual disability are high among leprosy patients in Nepal even after completing multidrug therapy.
Bhagavat P Nepal; Ujjowala D Shrestha
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  American journal of ophthalmology     Volume:  137     ISSN:  0002-9394     ISO Abbreviation:  Am. J. Ophthalmol.     Publication Date:  2004 May 
Date Detail:
Created Date:  2004-05-05     Completed Date:  2004-06-03     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0370500     Medline TA:  Am J Ophthalmol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  888-92     Citation Subset:  AIM; IM    
BP Koirala Lions Center for Ophthalmic Studies, PO Box 8750, Maharajgunj, Kathmandu, Nepal.
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MeSH Terms
Drug Therapy, Combination
Eye Diseases / drug therapy,  epidemiology*,  etiology
Leprostatic Agents / therapeutic use*
Leprosy / complications,  drug therapy*,  epidemiology*
Middle Aged
Nepal / epidemiology
Reg. No./Substance:
0/Leprostatic Agents

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