| Ocular complications of sigmoid sinus thrombosis from L-asparaginase. | |
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MedLine Citation:
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PMID: 15825749 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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This article presents a 9-year-old boy with acute lymphocytic leukemia who developed ocular complications after beginning treatment with L-asparaginase. Ocular motor examination revealed esotropia with a right abduction deficit, consistent with a sixth nerve palsy, and funduscopy revealed bilateral optic disc edema. Thrombosis of the right sigmoid sinus was noted on magnetic resonance imaging and magnetic resonance venography. Symptoms gradually resolved after discontinuing L-asparaginase and treatment with heparin. |
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Authors:
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Rod Foroozan |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Journal of pediatric ophthalmology and strabismus Volume: 42 ISSN: 0191-3913 ISO Abbreviation: J Pediatr Ophthalmol Strabismus Publication Date: 2005 Mar-Apr |
Date Detail:
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Created Date: 2005-04-13 Completed Date: 2005-04-26 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 7901143 Medline TA: J Pediatr Ophthalmol Strabismus Country: United States |
Other Details:
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Languages: eng Pagination: 117-9 Citation Subset: IM |
Affiliation:
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Neuro-Ophthalmology Service, Cullen Eye Institute, Baylor College of Medicine, Houston, Texas 77030, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Abducens Nerve Antineoplastic Agents / adverse effects*, therapeutic use Asparaginase / adverse effects*, therapeutic use Child Cranial Nerve Diseases / etiology Esotropia / etiology Eye Diseases / etiology* Fundus Oculi Humans Magnetic Resonance Angiography Magnetic Resonance Imaging Male Papilledema / diagnosis, etiology Precursor Cell Lymphoblastic Leukemia-Lymphoma / drug therapy* Sinus Thrombosis, Intracranial / chemically induced*, complications*, diagnosis |
| Chemical | |
Reg. No./Substance:
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0/Antineoplastic Agents; EC 3.5.1.1/Asparaginase |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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