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Ocular and cervical vestibular evoked myogenic potentials in multiple sclerosis patients.
MedLine Citation:
PMID:  22418590     Owner:  NLM     Status:  Publisher    
OBJECTIVE: Vestibular evoked myogenic potentials (VEMPs) are thought to provide useful information about brainstem functions, as the neural pathways of both ocular and cervical VEMPs pass through the brainstem. The aim of this study was to investigate the clinical value of ocular and cervical VEMP tests in the evaluation of brainstem involvement in multiple sclerosis (MS) patients and to assess their relation with clinical and cranial MRI findings. METHODS: Ocular and cervical VEMPs were recorded in 62 MS patients and 35 age and sex matched healthy volunteers. The latencies, amplitude asymmetry ratios of both VEMP responses and abnormality ratios (prolonged latencies and absent responses) were compared between the MS patients and the control group and among the groups of MS patients. RESULTS: oVEMP mean n1 and p1 latencies and cVEMP mean p13 latency were significantly prolonged in MS patients. Although the abnormality ratios of both VEMPs were higher in patients with brainstem clinical or MRI lesions, the correlation was not statistically significant. Both ocular and cervical VEMP latencies were significantly correlated with expanded disability status scale. CONCLUSIONS: Although there is no significant correlation with clinical or MRI findings, MS patients show high frequency of abnormality in VEMP tests, especially in oVEMP tests. SIGNIFICANCE: VEMP tests may be useful as an adjunct test in the evaluation of brainstem dysfunction in MS patients.
Sibel Gazioglu; Cavit Boz
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-3-12
Journal Detail:
Title:  Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology     Volume:  -     ISSN:  1872-8952     ISO Abbreviation:  -     Publication Date:  2012 Mar 
Date Detail:
Created Date:  2012-3-15     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100883319     Medline TA:  Clin Neurophysiol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2012 International Federation of Clinical Neurophysiology. Published by Elsevier Ireland Ltd. All rights reserved.
Department of Neurology, Karadeniz Technical University Medical Faculty, 61080 Trabzon, Turkey.
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