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Octreotide in the treatment of neonatal postoperative chylothorax: report of three cases and literature review.
MedLine Citation:
PMID:  20821216     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Chylothorax is a well-recognized complication after neonatal cardiothoracic surgery. Management strategies include cessation of enteral feedings, repeated aspiration, chest drainage, and total parenteral nutrition. Somatostatin and its analogue, octreotide, have been used with promising results. The authors present three cases of neonatal postoperative chylothorax in which octreotide was used. After literature review, we can say that octreotide is relatively safe, and may reduce clinical course and complications associated with neonatal postoperative chylothorax. One should be aware of possible association between octreotide and necrotizing enterocolitis. Prospective controlled trials supporting octreotide use are lacking.
Authors:
João Moreira-Pinto; Paula Rocha; Angélica Osório; Berta Bonet; Fátima Carvalho; Carlos Duarte; Luísa Oliveira
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Publication Detail:
Type:  Journal Article     Date:  2010-09-07
Journal Detail:
Title:  Pediatric surgery international     Volume:  27     ISSN:  1437-9813     ISO Abbreviation:  Pediatr. Surg. Int.     Publication Date:  2011 Aug 
Date Detail:
Created Date:  2011-07-15     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8609169     Medline TA:  Pediatr Surg Int     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  805-9     Citation Subset:  IM    
Affiliation:
Serviço de Cirurgia Pediátrica, Centro Hospitalar do Porto, Rua da Boavista, 827, 4050-111, Porto, Portugal, moreirapinto@gmail.com.
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