Document Detail

Octreotide improved the quality of life in a child with malignant bowel obstruction caused by peritoneal dissemination of colon cancer.
MedLine Citation:
PMID:  17208578     Owner:  NLM     Status:  MEDLINE    
This is a first pediatric case about the efficacy of octreotide for improving symptoms of malignant bowel obstruction. A 12-year-old boy was referred to our hospital for treatment of transverse colon cancer with peritoneal dissemination. A transverse colectomy was undertaken with postoperative adjuvant chemotherapy. Seven months later, severe abdominal symptoms occurred caused by incomplete bowel obstruction owing to tumor progression. The patient's quality of life decreased with a resultant disturbed mental condition. His parents sought to stop chemotherapy and for him to receive palliative care at home. We suggested nasogastric tube placement, but this was rejected. After obtaining informed consent, octreotide was administered intravenously. After 1 week, abdominal symptoms improved and the boy's complaints stopped. He had a good appetite and was able to eat small amounts of food. He was able to spend his final 2 months at home without nausea and in his family surroundings.
Hideki Watanabe; Yasuhiro Inoue; Keiichi Uchida; Yoshinaga Okugawa; Junichiro Hiro; Eiki Ojima; Minako Kobayashi; Chikao Miki; Masato Kusunoki
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of pediatric surgery     Volume:  42     ISSN:  1531-5037     ISO Abbreviation:  J. Pediatr. Surg.     Publication Date:  2007 Jan 
Date Detail:
Created Date:  2007-01-08     Completed Date:  2007-02-05     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0052631     Medline TA:  J Pediatr Surg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  259-60     Citation Subset:  IM    
Department of Gastrointestinal and Pediatric Surgery, Mie University Graduate School of Medicine, Mie, Tsu, Japan.
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MeSH Terms
Adenocarcinoma / complications*,  secondary
Colon, Transverse
Colonic Neoplasms / complications*,  pathology,  surgery
Fatal Outcome
Gastrointestinal Agents / therapeutic use*
Intestinal Obstruction / drug therapy*,  etiology
Octreotide / therapeutic use*
Palliative Care
Peritoneal Neoplasms / complications*,  secondary
Quality of Life
Reg. No./Substance:
0/Gastrointestinal Agents; 83150-76-9/Octreotide

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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