Document Detail


Ochronotic arthropathy: diagnosis and management: a rritical review.
MedLine Citation:
PMID:  22482092     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Alkaptonuria, a rare hereditary metabolic disorder, is characterized by accumulation of homogentisic acid in the connective tissues resulting from lack of the enzyme homogentisic acid oxidase. Ochronosis, dark pigmentation of connective tissues, is the musculoskeletal manifestation of alkaptonuria. In this article, we report the case of a 53-year-old man who had ochronotic arthropathy and advanced degenerative changes in the shoulders managed with bilateral total shoulder arthroplasty. Three-year follow-up results were satisfactory: good range of motion, no pain, and no signs of prosthesis loosening. Shoulder function was significantly improved after surgery, as documented by Constant scores. This case suggests that shoulder prosthesis results are not affected by alkaptonuria.
Authors:
Emmanouil Drakoulakis; Dimitrios Varvitsiotis; Georgioss Psarea; John Feroussis
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  American journal of orthopedics (Belle Mead, N.J.)     Volume:  41     ISSN:  1934-3418     ISO Abbreviation:  Am J. Orthop.     Publication Date:  2012 Feb 
Date Detail:
Created Date:  2012-04-06     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9502918     Medline TA:  Am J Orthop (Belle Mead NJ)     Country:  United States    
Other Details:
Languages:  eng     Pagination:  80-3     Citation Subset:  IM    
Affiliation:
Asclepieion Voulas, Athens, Greece.
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