| Ochronosis, arthroscopy of a black knee: a case report and review of the literature. | |
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MedLine Citation:
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PMID: 17899002 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Ochronotic arthropathy is a rare condition found in patients with alkaptonuria. Due to the accumulation of homogentisic acid, cartilages get a dark discoloration and become brittle and more vulnerable to mechanical stress (Centinus et al. Rheumatol Int 3:127-131, 2004; Hamdi et al. Int Orthop 23:122-125, 1999; Phornphutkul, N Engl J Med 347:2111-2121, 2002; Thacker, Arthroscopy 19:14-17, 2003). This case report is about a patient first diagnosed for ochronosis by arthroscopy of the knee. Her brother was having similar complaints during follow-up. Both patients were prescribed to take glucosamine and chondroitine. Although no report is found in the literature, regarding the success of this therapy in patients with ochronosis, both patients reported a positive effect on articular pain and daily activities. |
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Authors:
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Martijn Raaijmaakers; Franky Steenbrugge; Carl Dierickx |
Publication Detail:
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Type: Case Reports; Journal Article Date: 2007-09-25 |
Journal Detail:
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Title: Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA Volume: 16 ISSN: 0942-2056 ISO Abbreviation: Knee Surg Sports Traumatol Arthrosc Publication Date: 2008 Feb |
Date Detail:
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Created Date: 2008-02-01 Completed Date: 2008-06-24 Revised Date: 2009-10-05 |
Medline Journal Info:
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Nlm Unique ID: 9314730 Medline TA: Knee Surg Sports Traumatol Arthrosc Country: Germany |
Other Details:
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Languages: eng Pagination: 182-4 Citation Subset: IM |
Affiliation:
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Department of Orthopaedic Surgery and Traumatology, Algemeen Stedelijk Ziekenhuis, Merestraat 80, 9300, Aalst, Belgium. marraaij@hotmail.com |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Alkaptonuria
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diagnosis* Arthralgia / drug therapy, etiology Arthroscopy Cartilage, Articular / injuries, surgery Chondroitin / therapeutic use Female Glucosamine / therapeutic use Humans Knee Joint / pathology* Menisci, Tibial / injuries, surgery Middle Aged Ochronosis / etiology, pathology* Pain Measurement |
| Chemical | |
Reg. No./Substance:
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3416-24-8/Glucosamine; 9007-27-6/Chondroitin |
| Comments/Corrections | |
Comment In:
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Knee Surg Sports Traumatol Arthrosc. 2009 Oct;17(10):1270-1; author reply 1272-3
[PMID:
19756514
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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