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Occurrences of major polybrominated diphenyl ethers (PBDEs) in maternal and fetal cord blood sera in Korea.
MedLine Citation:
PMID:  24636800     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Polybrominated diphenyl ethers (PBDEs) are of growing public health concern because of their potential toxicities which range from endocrine disruption to neurodevelopment. However, information on their exposure among sensitive human populations is limited. The objectives of this study were to determine the levels of major PBDEs in blood sera of pregnant women and their matching newborn infants. For this purpose, a total of 198 maternal blood samples and 118 matching umbilical cord blood samples were collected from four regions of South Korea in 2011, and were determined for 19 PBDE congeners. Various demographic, dietary, and behavioral characteristics were asked in a questionnaire survey. Average concentration of total PBDEs in maternal blood serum was 3.34±8.42ng/g lipid weight (lw) at delivery and 3.14±7.46ng/g lw at 6months of pregnancy, respectively. In cord blood serum, an average of 9.37±12.60ng/g lw was detected. Among the measured PBDE congeners, BDE-47, BDE-99 and BDE-153 were most dominant in both maternal and cord blood sera. Relatively higher levels of BDE-99 were detected in cord blood serum. Strong positive correlations were detected between maternal and cord blood serum samples, indicating the importance of maternal transfer. Health consequences of transplacental exposure to PBDEs among fetuses and newborn infants warrant further investigation.
Authors:
Gyuyeon Choi; Sungjoo Kim; Sunmi Kim; Sungkyoon Kim; Youngeun Choi; Hai-Joong Kim; Jeong Jae Lee; Su Young Kim; Sunggyu Lee; Hyo-Bang Moon; Sooran Choi; Kyungho Choi; Jeongim Park
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2014-3-14
Journal Detail:
Title:  The Science of the total environment     Volume:  -     ISSN:  1879-1026     ISO Abbreviation:  Sci. Total Environ.     Publication Date:  2014 Mar 
Date Detail:
Created Date:  2014-3-18     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0330500     Medline TA:  Sci Total Environ     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2014 Elsevier B.V. All rights reserved.
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