Document Detail

Occurrence of minute ring-shaped nucleoprotein particles in culture media conditioned by mammalian cells.
MedLine Citation:
PMID:  955647     Owner:  NLM     Status:  MEDLINE    
Conditioned media of 21 mammalian cell lines have been examined by electron microscopic and biochemical techniques for the presence of a minute ring-shaped nucleoprotein particle (RSP). Electron microscopy showed the presence of RSP in 20 of the 21 cell lines tested. Comparative analyses of sex cell cultures for radioactive RSP, following 3H-thymidine incorporation, suggested that quantitative differences exist in the amount of RSP detectable in conditioned media of normal and pathologic cells. The cell lines tested included cells of different morphologies, origin and function
R Ashkenazi-Ezra; N Henderson
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  In vitro     Volume:  12     ISSN:  0073-5655     ISO Abbreviation:  In Vitro     Publication Date:  1976 Jun 
Date Detail:
Created Date:  1976-10-20     Completed Date:  1976-10-20     Revised Date:  2009-11-11    
Medline Journal Info:
Nlm Unique ID:  0063733     Medline TA:  In Vitro     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  436-41     Citation Subset:  IM    
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MeSH Terms
Cell Line*
Centrifugation, Density Gradient
Culture Media / analysis*
Microscopy, Electron
Nucleoproteins / analysis*
Ribonucleoproteins / analysis*
Reg. No./Substance:
0/Culture Media; 0/Nucleoproteins; 0/Ribonucleoproteins

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