| Occurrence of hepatocellular carcinoma after hepatoblastoma resection in an adult with hepatitis C virus. | |
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MedLine Citation:
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PMID: 19207587 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Hepatoblastoma is a rare malignancy in adults. It is often diagnosed after the appearance of symptoms, therefore, the tumor size tends to be larger. In patients with no indication for a hepatic resection, the prognosis of adult hepatoblastoma is quite poor. A 54-year-old man with hepatitis C virus-associated liver cirrhosis was initially treated with a hepatic resection for a hepatic tumor, 3 cm in diameter. The tumor consisted of osteoid-like and cartilaginous foci, myxomatous stroma, and poorly differentiated hepatocellular carcinomatous cells and was diagnosed as a mixed epithelial and mesenchymal hepatoblastoma. Two years after the first operation, multicentric hepatocellular carcinomas developed in the remnant liver and were successfully treated with a secondary hepatic resection combined with radio-frequency ablation. The patient is now alive with no recurrence at 5 years after the initial hepatectomy. To the best of our knowledge, the primary hepatoblastoma was the smallest such tumor reported and this is the first report of a metachronous hepatoblastoma and hepatocellular carcinoma in an adult hepatitis patient. |
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Authors:
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Toshiro Masuda; Toru Beppu; Kei Horino; Hiroyuki Komori; Hiromitsu Hayashi; Hirohisa Okabe; Ryuu Ootao; Hasita Horlad; Yoshifumi Baba; Shiho Miyase; Hiroshi Takamori; Hideo Baba |
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Publication Detail:
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Type: Journal Article Date: 2009-01-12 |
Journal Detail:
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Title: Hepatology research : the official journal of the Japan Society of Hepatology Volume: 39 ISSN: 1386-6346 ISO Abbreviation: Hepatol. Res. Publication Date: 2009 May |
Date Detail:
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Created Date: 2009-05-11 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9711801 Medline TA: Hepatol Res Country: Netherlands |
Other Details:
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Languages: eng Pagination: 525-30 Citation Subset: - |
Affiliation:
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Department of Gastroenterological Surgery, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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