Document Detail

Occurrence and detection of iron-deficiency anemia in infants and toddlers.
MedLine Citation:
PMID:  19174983     Owner:  NLM     Status:  MEDLINE    
Infants and toddlers are particularly vulnerable to developing iron deficiency, which can cause irreversible deficits in neurodevelopment. Children at highest risk include premature and low birth weight infants, those who are fed cow's milk rather than breast milk or formula prior to age one, and those who drink large amounts of cow's milk as toddlers. It is important to detect iron deficiency before it becomes frank anemia through the use of appropriate laboratory tests. Hemoglobin or hematocrit testing, at around age one, has been the usual screening test. These tests, however, do not become abnormally low until frank anemia has developed. Over the past decade, research has shown the assay for reticulocyte hemoglobin content to be a much earlier indicator of iron deficiency. This article provides an overview of the epidemiology, occurrence, and detection of iron deficiency and iron deficiency anemia in young children as well as a comparison of the utility of various laboratory tests.
Richard Bamberg
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Clinical laboratory science : journal of the American Society for Medical Technology     Volume:  21     ISSN:  0894-959X     ISO Abbreviation:  Clin Lab Sci     Publication Date:  2008  
Date Detail:
Created Date:  2009-01-29     Completed Date:  2009-02-19     Revised Date:  2009-04-09    
Medline Journal Info:
Nlm Unique ID:  8806547     Medline TA:  Clin Lab Sci     Country:  United States    
Other Details:
Languages:  eng     Pagination:  225-31     Citation Subset:  T    
Department of Clinical Laboratory Science, College of Allied Health Sciences, East Carolina University, Greenville, NC 27858-4353, USA.
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MeSH Terms
Anemia, Iron-Deficiency / diagnosis*,  epidemiology*
Child, Preschool
Erythrocyte Indices
Ferritins / blood
Infant, Newborn
Iron / blood
United States / epidemiology
Reg. No./Substance:
7439-89-6/Iron; 9007-73-2/Ferritins
Erratum In:
Clin Lab Sci. 2009 Winter;22(1):2

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