Document Detail

Occurrence of Rheumatoid Arthritis Requiring Oral and/or Biological Disease-Modifying Antirheumatic Drug Therapy Following a Diagnosis of Primary Sjögren Syndrome.
MedLine Citation:
PMID:  23013848     Owner:  NLM     Status:  Publisher    
ABSTRACT: We report 6 patients with an established diagnosis of primary Sjögren syndrome who developed severe rheumatoid arthritis (RA) requiring oral disease-modifying antirheumatic drug with or without biologic therapy. Rheumatoid arthritis was diagnosed between 14 months and 17 years following initial sicca symptoms. Five patients were female. Two thirds were seropositive for Sjögren antibody, and 5 of 6 were either rheumatoid factor or anti-cyclic citrullinated peptide positive at the time of RA diagnosis. All had either hand or wrist involvement; one third had nodules. Although none demonstrated erosion on x-ray, all required methotrexate or leflunomide, and 4 required a biologic agent for the treatment of their arthritis. Primary Sjögren patients may develop RA after a long course of stable Sjögren.
Omar Khan; Steven Carsons
Related Documents :
22186978 - Comparison of the yield and miss rate of narrow band imaging and white light endoscopy ...
21990438 - Solitaire fr thrombectomy system: immediate results in 56 consecutive acute ischemic st...
10458348 - Is transurethral biopsy of the bladder necessary after 3 months to evaluate response to...
20412398 - Clinicopathological features and immunohistochemical expression of p53, ki-67, mcm-2 an...
6838178 - How often does a csf pleocytosis follow generalized convulsions?
11269678 - Initial remission-inducing effect of very low-dose cyclosporin monotherapy for minimal-...
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-9-25
Journal Detail:
Title:  Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases     Volume:  -     ISSN:  1536-7355     ISO Abbreviation:  J Clin Rheumatol     Publication Date:  2012 Sep 
Date Detail:
Created Date:  2012-9-27     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9518034     Medline TA:  J Clin Rheumatol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
From the Division of Rheumatology, Allergy and Immunology Winthrop-University Hospital, Stony Brook University School of Medicine, Mineola, NY.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Subacromial bursitis with giant rice bodies as initial presentation of rheumatoid arthritis.
Next Document:  Wait Times for Rheumatology Consultation: Is Rheumatoid Arthritis Prioritized?