| Occupational rhinitis and asthma due to EDTA-containing detergents or disinfectants. | |
| | |
MedLine Citation:
|
PMID: 22431256 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
BACKGROUND: Detergents and disinfectants are an emerging cause of work-related rhinitis and asthma. These products may contain ethylenediamine tetraacetic acid (EDTA). The authors report 10 cases of EDTA-related asthma and/or rhinitis. METHODS: Review of the medical charts of patients who presented with work-related rhinitis (alone or with asthma), with a history of exposure to aerosols of EDTA-containing products and who underwent a nasal provocation test (NPT) with tetrasodium EDTA (1-4%) in our occupational health unit. RESULTS: Twenty-eight patients underwent a NPT with EDTA, which was positive in 10 cases. These patients, mostly cleaners or healthcare workers, used spray formulations of cleaning products. CONCLUSIONS: This case series is the first report of EDTA-related respiratory disease, documented by a specific test. An irritant mechanism is unlikely. Further studies are required to distinguish between an immunoallergic response and a pharmacological mechanism possibly resulting from calcium chelation, as suggested by animal experiments. A ban of spray preparations would be sufficient to prevent respiratory disease induced by EDTA inhalation, regardless of its mechanism. Am. J. Ind. Med. © 2012 Wiley Periodicals, Inc. |
| | |
Authors:
|
Hervé Laborde-Castérot; Antoine F Villa; Nicole Rosenberg; Patricia Dupont; Hwee Min Lee; Robert Garnier |
Related Documents
:
|
2656026 - Juxtacortical liposarcoma. a case report and review of the literature. 8020846 - Alveolar soft part sarcoma of the uterus: case report and review of the literature. 3962596 - Gliomyosarcoma. report of a case of rhabdomyosarcoma arising in a malignant glioma. 16673556 - (18)fdg-pet-scan in staging of primary malignant melanoma of the oesophagus: a case rep... 19264366 - A systematic review of concomitant interventions to prevent persistent perforations fol... 10585076 - Common arterial trunk associated with double aortic arch. |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2012-3-16 |
Journal Detail:
|
Title: American journal of industrial medicine Volume: - ISSN: 1097-0274 ISO Abbreviation: - Publication Date: 2012 Mar |
Date Detail:
|
Created Date: 2012-3-20 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 8101110 Medline TA: Am J Ind Med Country: - |
Other Details:
|
Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
|
Copyright © 2012 Wiley Periodicals, Inc. |
Affiliation:
|
AP-HP, Paris Poison Centre, Occupational and Environmental Health Unit, Fernand Widal Hospital, Paris, France. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: What Is the Maximum Coordination Number in a Planar Structure?
Next Document: Trends in adolescent eating behaviour: a multilevel cross-sectional study of 11-15 year olds in Scot...