| Occupational hydrocarbon exposure and risk of renal cell carcinoma. | |
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MedLine Citation:
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PMID: 2729279 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A population-based case-control study (210 cases and 210 age- sex- and frequency-matched population controls) was conducted to evaluate the association between occupational hydrocarbon exposure and risk of renal cell carcinoma. Retrospective estimates of lifetime occupational hydrocarbon exposure were made without regard to case or control status, and an exposure index was calculated based on time and score combinations. A weak positive association was found for hydrocarbon exposure in males only (odds ratio = 1.6). For those under the age of 60, exposure to moderate levels of hydrocarbons produced the highest risk, while for those over the age of 70 a dose-response relationship was found. Those overweight were at high risk for renal cell carcinoma, and there was positive interaction between hydrocarbon exposure and overweight. Alcohol use alone or in the presence of hydrocarbon exposure decreased the risk significantly. |
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Authors:
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S Kadamani; N R Asal; R Y Nelson |
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Publication Detail:
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Type: Journal Article; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: American journal of industrial medicine Volume: 15 ISSN: 0271-3586 ISO Abbreviation: Am. J. Ind. Med. Publication Date: 1989 |
Date Detail:
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Created Date: 1989-06-29 Completed Date: 1989-06-29 Revised Date: 2007-11-14 |
Medline Journal Info:
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Nlm Unique ID: 8101110 Medline TA: Am J Ind Med Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 131-41 Citation Subset: IM |
Affiliation:
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Department of Biostatistics and Epidemiology, College of Public Health, University of Oklahoma, Oklahoma City. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Aged, 80 and over Carcinoma, Renal Cell / chemically induced*, epidemiology Female Humans Hydrocarbons / adverse effects* Kidney Neoplasms / chemically induced* Male Middle Aged Occupational Diseases / chemically induced*, epidemiology Risk Factors |
| Grant Support | |
ID/Acronym/Agency:
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1-R01-CA31059-0104/CA/NCI NIH HHS |
| Chemical | |
Reg. No./Substance:
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0/Hydrocarbons |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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