| Occupational exposures and chronic respiratory symptoms. A population-based study. | |
| | |
MedLine Citation:
|
PMID: 3497594 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Data from a random sample of 8,515 white adults residing in 6 cities in the eastern and midwestern United States were used to examine the relationships between occupational exposures to dust or to gases and fumes and chronic respiratory symptoms; 31% of the population had a history of occupational dust exposure and 30% reported exposure to gas or fumes. After adjusting for smoking habits, age, gender, and city of residence, subjects with either occupational exposure had significantly elevated prevalences of chronic cough, chronic phlegm, persistent wheeze, and breathlessness. The adjusted relative odds of chronic respiratory symptoms for subjects exposed to dust ranged from 1.32 to 1.60. Subjects with gas or fume exposure had relative odds of symptoms between 1.27 and 1.43 when compared with unexposed subjects. Occupational dust exposure was associated with a higher prevalence of chronic obstructive pulmonary disease as defined by an FEV1/FVC ratio of less than 0.6, when comparing exposed and unexposed participants (OR = 1.53, 95% Cl = 1.17-2.08). Gas or fume exposure was associated with a small, but not significant, increase in COPD prevalence. Significant trends were noted for wheeze and phlegm with increasing duration of dust exposure. Although 36% of exposed subjects reported exposure to both dust and fumes, there was no evidence of a multiplicative interaction between the effects of the individual exposures. Smoking was a significant independent predictor of symptoms, but did not appear to modify the effect of dust or fumes on symptom reporting. These data, obtained in random samples of general populations, demonstrate that chronic respiratory symptoms and disease can be independently associated with occupational exposures. |
| | |
Authors:
|
R J Korn; D W Dockery; F E Speizer; J H Ware; B G Ferris |
Related Documents
:
|
8543474 - Some aspects of occupational safety and health in green tea workers. 8473704 - Evidence for a preretirement process among older male workers. 16841244 - Lead intoxication: a summary of the clinical presentation among thai patients. 3970884 - Gassings due to methylene chloride, xylene, toluene, and styrene reported to her majest... 18629624 - Sex differences in wisc-iii profiles of children with high-functioning pervasive develo... 15251294 - Theoretical models to evaluate hazard due to organochlorine compounds (ocs) in mediterr... |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
|
Title: The American review of respiratory disease Volume: 136 ISSN: 0003-0805 ISO Abbreviation: Am. Rev. Respir. Dis. Publication Date: 1987 Aug |
Date Detail:
|
Created Date: 1987-09-17 Completed Date: 1987-09-17 Revised Date: 2007-11-14 |
Medline Journal Info:
|
Nlm Unique ID: 0370523 Medline TA: Am Rev Respir Dis Country: UNITED STATES |
Other Details:
|
Languages: eng Pagination: 298-304 Citation Subset: AIM; IM |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Aged Air Pollutants, Occupational / adverse effects* Chronic Disease Cross-Sectional Studies Dust / adverse effects Environmental Exposure* Female Gases / adverse effects Humans Lung Diseases, Obstructive / etiology Male Middle Aged Respiratory Tract Diseases / chemically induced* Smoking |
| Grant Support | |
ID/Acronym/Agency:
|
ES-0002/ES/NIEHS NIH HHS; ES-01108/ES/NIEHS NIH HHS; HL-07477/HL/NHLBI NIH HHS |
| Chemical | |
Reg. No./Substance:
|
0/Air Pollutants, Occupational; 0/Dust; 0/Gases |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Comparative immunoelectrophoretic studies of total water-soluble extracts of Trichomonas vaginalis, ...
Next Document: The neuropsychiatric effects of treatment with interleukin-2 and lymphokine-activated killer cells.