| Occupational exposure to UV light and mortality from multiple sclerosis. | |
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MedLine Citation:
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PMID: 19197935 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: The etiology of multiple sclerosis (MS) is largely unknown; low exposure to ultraviolet (UV) light has been a suggested risk factor. The aim of this study was to investigate whether occupational exposure to UV light reduces the risk of death from MS. METHODS: The cohort was based on all individuals in the Swedish census in 1980. All MS-related deaths were identified in the national registry of causes of death. A job-exposure matrix was developed to classify the occupational exposure to UV light. RESULTS: MS was recorded as a cause of the death for 839 individuals. The risk of MS-related death decreased with increasing occupational exposure to UV light. The relative risk adjusted for age, sex, and socioeconomic status was 0.48 (95% CI 0.28-0.80) in the high-exposure group and 0.88 (95% CI 0.73-1.06) in the intermediate-exposure group. CONCLUSIONS: Occupational exposure to UV light was associated with a reduced risk of MS. Our findings are corroborated by previous observations that UV light has a preventive role in the development of MS, although the possibility of reversed causality cannot be completely ruled out. |
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Authors:
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M Westberg; M Feychting; F Jonsson; G Nise; P Gustavsson |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: American journal of industrial medicine Volume: 52 ISSN: 1097-0274 ISO Abbreviation: Am. J. Ind. Med. Publication Date: 2009 May |
Date Detail:
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Created Date: 2009-04-09 Completed Date: 2009-06-09 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8101110 Medline TA: Am J Ind Med Country: United States |
Other Details:
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Languages: eng Pagination: 353-7 Citation Subset: IM |
Copyright Information:
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Copyright 2009 Wiley-Liss, Inc. |
Affiliation:
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Department of Occupational and Environmental Health, Stockholm Centre for Public Health, Stockholm, Sweden. mattias_westberg@hotmail.com |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Causality Cause of Death* Environmental Monitoring* Female Humans Male Middle Aged Multiple Sclerosis / etiology, mortality* Occupational Exposure / adverse effects*, statistics & numerical data* Risk Factors Socioeconomic Factors Sweden / epidemiology Ultraviolet Rays / adverse effects* Young Adult |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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