Document Detail

Occupational asbestos exposure as a risk factor for laryngeal carcinoma in a population-based case-control study from Germany.
MedLine Citation:
PMID:  21538446     Owner:  NLM     Status:  Publisher    
BACKGROUND: As several studies have identified asbestos exposure as an independent occupational risk factor for laryngeal cancer, the aim of our study was to confirm this association. METHODS: In a population-based case-control study on laryngeal cancer in South-West Germany occupational exposures and other risk factors were obtained by face-to-face interviews using a detailed standardized questionnaire covering the complete individual working history, supplemented by job-specific questionnaires (JSQ) especially for selected jobs known to entail exposure to asbestos. Detailed exposure information was collected over a wide range of asbestos related jobs and branches and analyzed using different modeling strategies. RESULTS: Seventy-three (28.4%) cases and 158 (20.5%) controls reported any exposure to asbestos. Elevated risk estimates for asbestos exposure were found. However, those became substantially reduced after adjustment for smoking and alcohol. CONCLUSION: Moderately elevated risks for laryngeal cancer after exposure to asbestos were confirmed. Difficulties in the collection of adequate exposure data were demonstrated. Am. J. Ind. Med. © 2011 Wiley-Liss, Inc.
Heribert Ramroth; Wolfgang Ahrens; Andreas Dietz; Heiko Becher
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-5-2
Journal Detail:
Title:  American journal of industrial medicine     Volume:  -     ISSN:  1097-0274     ISO Abbreviation:  -     Publication Date:  2011 May 
Date Detail:
Created Date:  2011-5-3     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8101110     Medline TA:  Am J Ind Med     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2011 Wiley-Liss, Inc.
Institute of Public Health, University of Heidelberg, Heidelberg, Germany.
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