| Occupational allergy to wheat flour. Nasal response to specific inhalative challenge in asthma and rhinitis vs. isolated rhinitis: a comparative study. | |
| | |
MedLine Citation:
|
PMID: 15852757 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
OBJECTIVES: The purpose of the study was to compare cytological and biochemical changes in nasal lavage fluid induced by wheat flour inhalatory challenge in bakers with allergic rhinitis and with asthma accompanied by rhinitis. MATERIALS AND METHODS: A single-blind, placebo controlled study was conducted in 64 bakers with allergic rhinitis (n = 17), bronchial asthma and rhinitis (n = 24) and without occupational allergy (n = 23). Nasal washings were examined before, 30 min, 4 and 24 h after the specific provocation, wheras non-specific bronchial hyperreactivity (PC20) before and after 24 h. RESULTS: A significant decrease in PC20 after the challenge test was observed only in patients with asthma and rhinitis. Eosinophil count and percentage, basophil count and the permeability index induced by specific provocation were significantly increased in both rhinitis patients and asthmatics. Moreover, the increase especially in total count and proportion of eosinophils as well as in the permeability index was more pronounced in subjects suffering from asthma and rhinitis than in those with rhinitis alone, although the changes were not statistically significant. CONCLUSIONS: The results indicate the applicability of the "nasal pool" technique as a simple diagnostic procedure in flour-induced airway allergy. However, the evaluation of nasal lavage fluid, although a very sensitive and specific method of diagnosing respiratory allergic disease, cannot be used to distinguish patients with upper and lower airway allergy. |
| | |
Authors:
|
Jolanta Walusiak; Marta Wiszniewska; Patrycja Krawczyk-Adamus; Cezary Pałczyński |
Related Documents
:
|
7498637 - Perception and reflex responses to intestinal distention in humans are modified by simu... 16137527 - Biofeedback training of nasal muscles using internal and external surface electromyogra... 9186837 - In vitro effects of cholecystokinin fragments on human gallbladders. evidence for an al... 18530657 - A comparative study of four concert halls in istanbul: correlation of subjective evalua... 7701507 - Relationship between physical exercise and health of the elderly people in a rural comm... 2087577 - Cardiovascular complications of inactivity. |
Publication Detail:
|
Type: Clinical Trial; Comparative Study; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
|
Title: International journal of occupational medicine and environmental health Volume: 17 ISSN: 1232-1087 ISO Abbreviation: Int J Occup Med Environ Health Publication Date: 2004 |
Date Detail:
|
Created Date: 2005-04-27 Completed Date: 2005-06-10 Revised Date: 2006-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 9437093 Medline TA: Int J Occup Med Environ Health Country: Poland |
Other Details:
|
Languages: eng Pagination: 433-40 Citation Subset: IM |
Affiliation:
|
Department of Occupational Diseases and Occupational and Environmental Allergy Centre, Nofer Institute of Occupational Medicine, Lódź, Poland. jolantaw@imp.lodz.pl |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Air Pollutants, Occupational / adverse effects* Asthma / diagnosis*, etiology Female Flour / adverse effects* Humans Immunoglobulin E / blood Male Middle Aged Nasal Lavage Fluid / immunology* Nasal Provocation Tests Occupational Exposure / adverse effects* Rhinitis, Allergic, Perennial / diagnosis*, etiology Single-Blind Method Triticum / adverse effects* |
| Chemical | |
Reg. No./Substance:
|
0/Air Pollutants, Occupational; 37341-29-0/Immunoglobulin E |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Vagus nerve participates in regulation of the airways: inflammatory response and hyperreactivity ind...
Next Document: Respiratory complaints and medication use following cessation of exposure to construction dust and d...