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Occupational Mobility and Carotid Artery Intima-Media Thickness: Findings From the Coronary Artery Risk Development in Young Adults Study.
MedLine Citation:
PMID:  22021461     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
ObjectiveTo examine whether a 10-year change in occupational standing is related to carotid artery intima-media thickness (IMT) 5 years later.MethodsData were obtained from 2350 participants in the Coronary Artery Risk Development in Young Adults (CARDIA) Study. Occupational standing was measured at the Year 5 and 15 CARDIA follow-up examinations when participants were 30.2 (standard deviation = 3.6) and 40.2 (standard deviation = 3.6) years of age, respectively. IMT (common carotid artery [CCA], internal carotid artery [ICA], and bulb) was measured at Year 20. Occupational mobility was defined as the change in occupational standing between Years 5 and 15 using two semicontinuous variables. Analyses controlled for demographics, CARDIA center, employment status, parents' medical history, own medical history, Year 5 Framingham Risk Score, physiological risk factors and health behaviors averaged across the follow-up, and sonography reader.ResultsOccupational mobility was unrelated to IMT save for an unexpected association of downward mobility with less CCA-IMT (β = -0.04, p = .04). However, associations differed depending on initial standing (Year 5) and sex. For those with lower initial standings, upward mobility was associated with less CCA-IMT (β = -0.07, p = .003), and downward mobility was associated with greater CCA-IMT and bulb-ICA-IMT (β = 0.14, p = .01 and β = 0.14, p = .03, respectively); for those with higher standings, upward mobility was associated with greater CCA-IMT (β = 0.15, p = .008), but downward mobility was unrelated to either IMT measure (p values > .20). Sex-specific analyses revealed associations of upward mobility with less CCA-IMT and bulb-ICA-IMT among men only (p values < .02).ConclusionsOccupational mobility may have implications for future cardiovascular health. Effects may differ depending on initial occupational standing and sex.
Authors:
Denise Janicki-Deverts; Sheldon Cohen; Karen A Matthews; David R Jacobs; Nancy E Adler
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-10-21
Journal Detail:
Title:  Psychosomatic medicine     Volume:  -     ISSN:  1534-7796     ISO Abbreviation:  -     Publication Date:  2011 Oct 
Date Detail:
Created Date:  2011-10-24     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0376505     Medline TA:  Psychosom Med     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Department of Psychology (D.J.-D., S.C.), Carnegie Mellon University; and Department of Psychiatry (K.A.M.), University of Pittsburgh, Pittsburgh, Pennsylvania; Division of Epidemiology and Community Health (D.R.J.), School of Public Health, University of Minnesota, Minneapolis, Minnesota; Department of Nutrition (D.R.J.), University of Oslo, Oslo, Norway; and Department of Psychiatry (N.E.A.), University of California, San Francisco, California.
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