Document Detail

Occlusive thromboaortopathy (Takayasu's disease) and pregnancy. Clinical course and management of 33 pregnancies and deliveries.
MedLine Citation:
PMID:  6128919     Owner:  NLM     Status:  MEDLINE    
Twenty-seven Japanese patients with occlusive thromboaortopathy (Takayasu's disease) associated with 33 pregnancies and deliveries were followed up prospectively, from the prepregnant period. Inflammatory activity of the disease was apparently not enhanced by the pregnancy, but various cardiovascular-related events occurred in the perinatal period. During the intrapartum uterine contractions, marked elevation of systolic blood pressure was associated with 10 pregnancies, including 1 case of subsequent cerebral hemorrhage; this did not occur in 13 normal control gravidas. There were no maternal or neonatal deaths. The birth weight of 25 infants of 21 patients without complications or with a mild single complication of Takayasu's disease was 3,023 +/- 442 g (mean +/- standard deviation). The birth weight of 8 infants of 6 patients who had a severe single complication or multiple complications of the disease was 2,599 +/- 394 g (p less than 0.05). Of 83 pregnancies, the present 33 plus 50 other reported cases there were no un-toward events in two fifths. Three fifths had various problems, most of which were related to pressure elevation and heart failure, including intrapartum cerebral hemorrhage in 4. These data should assist in predicting the outcome of pregnancy and delivery in patients with Takayasu's disease.
K Ishikawa; S Matsuura
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The American journal of cardiology     Volume:  50     ISSN:  0002-9149     ISO Abbreviation:  Am. J. Cardiol.     Publication Date:  1982 Dec 
Date Detail:
Created Date:  1983-01-07     Completed Date:  1983-01-07     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0207277     Medline TA:  Am J Cardiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1293-300     Citation Subset:  AIM; IM    
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MeSH Terms
Aortic Arch Syndromes / complications*
Birth Weight
Cerebral Hemorrhage / etiology
Delivery, Obstetric / methods
Hypertension / etiology
Infant, Newborn
Labor, Obstetric
Maternal Age
Pregnancy Complications, Cardiovascular / diagnosis*
Takayasu Arteritis / complications*,  diagnosis,  therapy

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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