Document Detail


Occipital lobe seizures related to clinically asymptomatic celiac disease in adulthood.
MedLine Citation:
PMID:  1592023     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We report the electroclinical ictal findings of four epileptic patients with clinically asymptomatic celiac disease (CD). Celiac disease diagnosis was suspected by past history and/or computed tomography (CT) findings in all patients and confirmed by laboratory tests and jejunal biopsy. All patients had paroxysmal visual manifestations and ictal EEG discharges arising from the occipital lobe. Epilepsy evolution was favorable in two patients and severe in 2, regardless of CT evidence of occipital corticosubcortical calcifications in 2 patients. Occipital lobe seizures may be characteristic of the epilepsy related to CD, and epileptic patients with these seizures of unknown etiology should be carefully investigated for malabsorption. If past history and/or laboratory tests suggest gastrointestinal (GI) dysfunction they should also undergo small intestinal biopsy even if they do not have GI tract symptoms.
Authors:
G Ambrosetto; L Antonini; C A Tassinari
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Epilepsia     Volume:  33     ISSN:  0013-9580     ISO Abbreviation:  Epilepsia     Publication Date:    1992 May-Jun
Date Detail:
Created Date:  1992-07-01     Completed Date:  1992-07-01     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  2983306R     Medline TA:  Epilepsia     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  476-81     Citation Subset:  IM    
Affiliation:
Institute of Neurology, University of Bologna, Italy.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Biopsy
Brain Diseases / etiology,  pathology
Calcinosis / radiography
Celiac Disease / complications*,  pathology,  radiography
Electroencephalography
Female
Humans
Jejunum / pathology
Male
Occipital Lobe / pathology,  physiopathology*
Seizures / etiology*,  physiopathology
Tomography, X-Ray Computed

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