| Obstructive sleep apnoea in patients with obesity and hypertension. | |
| | |
MedLine Citation:
|
PMID: 20423584 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
BACKGROUND: The links between obstructive sleep apnoea and hypertension are well established; obstructive sleep apnoea is reported in up to 30% of patients with hypertension, although it is frequently underdiagnosed. Physicians can assess the degree of sleepiness by administering the Epworth Sleepiness Scale, but the large number of patients with hypertension makes this strategy difficult for busy physicians to implement. Obese patients form a subgroup at higher risk for obstructive sleep apnoea, which can be targeted for screening. AIM: The study carried out a preliminary exploration of the effectiveness of screening patients with hypertension and obesity for obstructive sleep apnoea in general practice using the Epworth Sleepiness Scale. SETTING: One group practice in Italy. DESIGN OF STUDY: 'Good clinical practice' was systematically applied: identification of patients with hypertension and obesity; qualitative interview to identify obstructive sleep apnea; and consequent work-up and therapy. METHOD: Three family physicians, caring for 769 pharmacologically-treated patients with hypertension, identified 220 obese patients without relevant pulmonary or neurological diseases or insomnia; 31 of these 220 patients scored >11 on the Epworth Sleepiness Scale. RESULTS: Polysomnography confirmed obstructive sleep apnoea in 10% of the obese, hypertensive population (95% confidence interval [CI] = 7.03% to 13.63%), and in 3.9% of the whole hypertensive population (95% CI = 2.74% to 5.51%). At baseline, 24-hour blood pressure monitoring showed uncontrolled blood pressure in all these patients. Under continuous positive airway pressure (CPAP), the blood pressure value normalised (P<0.05), and the mean Epworth Sleepiness Scale score decreased significantly: mean 13.68 versus 7.84 (P<0.001). CONCLUSION: In obese patients with hypertension examined in this study, the prevalence of obstructive sleep apnoea prevalence is about 10%. CPAP significantly ameliorates the blood pressure control. This simple screening and treatment strategy may be easily adopted in primary care. |
| | |
Authors:
|
Antonino Di Guardo; Gaetano Profeta; Cristiano Crisafulli; Giuseppe Sidoti; Marcello Zammataro; Italo Paolini; Alessandro Filippi |
Related Documents
:
|
7468574 - Behavioral factors and blood pressure in adolescence: the tacoma study. 22346574 - Sensing pressure distribution on a lower-limb exoskeleton physical human-machine interf... 20348094 - Obesity-induced hypertension: role of sympathetic nervous system, leptin, and melanocor... 10067794 - An independent relationship between plasma leptin and heart rate in untreated patients ... 18984944 - Continuous positive airway pressure and liver enzymes in obstructive sleep apnoea: data... 16705254 - Sublingual capnometry: a non-invasive measure of microcirculatory dysfunction and tissu... |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: The British journal of general practice : the journal of the Royal College of General Practitioners Volume: 60 ISSN: 1478-5242 ISO Abbreviation: Br J Gen Pract Publication Date: 2010 May |
Date Detail:
|
Created Date: 2010-04-28 Completed Date: 2010-12-20 Revised Date: 2011-07-28 |
Medline Journal Info:
|
Nlm Unique ID: 9005323 Medline TA: Br J Gen Pract Country: England |
Other Details:
|
Languages: eng Pagination: 325-8 Citation Subset: IM |
Affiliation:
|
Italian College of General Practitioners, Via del Pignoncino 9/11, Florence, Italy. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adolescent Adult Aged Continuous Positive Airway Pressure Female Humans Hypertension / complications*, drug therapy Male Middle Aged Obesity / complications* Polysomnography Sleep Apnea, Obstructive / etiology*, therapy Young Adult |
| Comments/Corrections | |
Comment In:
|
Br J Gen Pract. 2010 May;60(574):319-20
[PMID:
20423581
]
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Family history in primary care: understanding GPs' resistance to clinical genetics--qualitative stud...
Next Document: Healthcare use in adults with insomnia: a longitudinal study.