| Obstructive sleep apnea syndrome: are we missing an at-risk population? | |
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MedLine Citation:
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PMID: 17564406 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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STUDY OBJECTIVES: While age and body-mass index (BMI) are well-established risk factors for obstructive sleep apnea syndrome (OSAS), this disorder occurs across a wide spectrum of ages and weights. Preconceptions regarding "classic" patients with OSAS may lead to underdiagnosis in at-risk populations, particularly younger nonoverweight individuals. We hypothesized that the severity of OSAS is independent of age and BMI in a younger less-obese population. METHODS: Prospective study of consecutive patients diagnosed with OSAS. Active-duty military, National Guardsmen, and civilians were compared to determine if age and BMI correlated with disease severity. RESULTS: Two hundred seventy subjects (120 active-duty, 80 National Guardsmen, 70 civilians) were included. Active-duty military members were significantly younger and less overweight than both National Guardsmen and civilians. Of the civilians, 64.3% and, of National Guardsmen, 48.8% were obese, whereas only 19.2% of active-duty had a BMI > or = 30 kg/m2 (p < .001). However, the prevalence of severe disease did not differ between groups. Disease severity showed no correlation with BMI among active-duty subjects (r = 0.09, p = .33). Of the active-duty subjects, 37.5% had severe disease, as compared with 42.5% of National Guard and 45.7% of civilian subjects (p = .18 and .09, respectively). BMI did not differ between active-duty subjects with severe disease and those with mild to moderate OSAS (26.7 kg/m2 versus 26.9 kg/m2, p = .40). There was a low but significant correlation between age and AHI (r = 0.21, p = .02) among all subjects. CONCLUSIONS: OSAS occurs in young nonobese individuals and should be considered in patients reporting excessive daytime sleepiness, regardless of age or BMI. |
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Authors:
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Christopher J Lettieri; Am H Eliasson; Teotimo Andrada; Andrei Khramtsov; Marc Raphaelson; David A Kristo |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine Volume: 1 ISSN: 1550-9389 ISO Abbreviation: - Publication Date: 2005 Oct |
Date Detail:
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Created Date: 2007-06-13 Completed Date: 2007-07-26 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101231977 Medline TA: J Clin Sleep Med Country: United States |
Other Details:
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Languages: eng Pagination: 381-5 Citation Subset: IM |
Affiliation:
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Pulmonary, Critical Care and Sleep Medicine Service, Walter Reed Army Medical Center, Washington, DC 20307, USA. christopher.lettieri@us.army.mil |
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Body Mass Index Demography Female Humans Male Middle Aged Obesity / epidemiology Polysomnography Prevalence Prospective Studies Risk Factors Severity of Illness Index Sleep Apnea, Obstructive / diagnosis*, epidemiology |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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