Document Detail


Obstructive sleep apnea and hypertension.
MedLine Citation:
PMID:  16256012     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
There is growing evidence of a causal relationship between obstructive sleep apnea (OSA) and hypertension. Untreated OSA may have direct and deleterious effects on cardiovascular function and structure through several mechanisms, including sympathetic activation, oxidative stress, inflammation, and endothelial dysfunction. OSA may contribute to or augment elevated blood pressure levels in a large proportion of the hypertensive patient population. It is important to consider OSA in the differential diagnosis of hypertensive patients who are obese. OSA should be especially considered in those hypertensive patients who respond poorly to combination therapy with antihypertensive medications.
Authors:
Krzysztof Narkiewicz; Jacek Wolf; Francisco Lopez-Jimenez; Virend K Somers
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Current cardiology reports     Volume:  7     ISSN:  1523-3782     ISO Abbreviation:  Curr Cardiol Rep     Publication Date:  2005 Nov 
Date Detail:
Created Date:  2005-10-31     Completed Date:  2006-01-20     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100888969     Medline TA:  Curr Cardiol Rep     Country:  United States    
Other Details:
Languages:  eng     Pagination:  435-40     Citation Subset:  IM    
Affiliation:
Hypertension Unit, Department of Hypertension and Diabetology, Medical University of Gdansk, Debinki 7c, 80-952 Gdansk, Poland. knark@amg.gda.pl
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MeSH Terms
Descriptor/Qualifier:
Animals
Blood Pressure / physiology
Endothelium, Vascular / physiopathology
Humans
Hypertension / epidemiology,  etiology*,  physiopathology
Incidence
Risk Factors
Sleep Apnea, Obstructive / complications*,  epidemiology,  physiopathology
United States / epidemiology
Vasoconstriction / physiology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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