| Obstructive sleep apnea and hypertension. | |
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MedLine Citation:
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PMID: 16256012 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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There is growing evidence of a causal relationship between obstructive sleep apnea (OSA) and hypertension. Untreated OSA may have direct and deleterious effects on cardiovascular function and structure through several mechanisms, including sympathetic activation, oxidative stress, inflammation, and endothelial dysfunction. OSA may contribute to or augment elevated blood pressure levels in a large proportion of the hypertensive patient population. It is important to consider OSA in the differential diagnosis of hypertensive patients who are obese. OSA should be especially considered in those hypertensive patients who respond poorly to combination therapy with antihypertensive medications. |
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Authors:
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Krzysztof Narkiewicz; Jacek Wolf; Francisco Lopez-Jimenez; Virend K Somers |
Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Current cardiology reports Volume: 7 ISSN: 1523-3782 ISO Abbreviation: Curr Cardiol Rep Publication Date: 2005 Nov |
Date Detail:
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Created Date: 2005-10-31 Completed Date: 2006-01-20 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 100888969 Medline TA: Curr Cardiol Rep Country: United States |
Other Details:
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Languages: eng Pagination: 435-40 Citation Subset: IM |
Affiliation:
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Hypertension Unit, Department of Hypertension and Diabetology, Medical University of Gdansk, Debinki 7c, 80-952 Gdansk, Poland. knark@amg.gda.pl |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Animals Blood Pressure / physiology Endothelium, Vascular / physiopathology Humans Hypertension / epidemiology, etiology*, physiopathology Incidence Risk Factors Sleep Apnea, Obstructive / complications*, epidemiology, physiopathology United States / epidemiology Vasoconstriction / physiology |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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