Document Detail

Obstructive sleep apnea is highly prevalent and correlates with impaired glycemic control in consecutive patients with the metabolic syndrome.
MedLine Citation:
PMID:  19614795     Owner:  NLM     Status:  MEDLINE    
Obstructive sleep apnea (OSA) and the metabolic syndrome (MS) are independently associated with increased cardiovascular risk. The objective of the present study was to determine the prevalence of OSA among consecutive patients with MS and to determine whether OSA is associated with impaired glycemic control. Fifty consecutive patients with a recent diagnosis of MS and no previous diagnosis of OSA underwent a polysomnography and anthropometric and laboratory measurements. The prevalence of OSA (apnea-hypopnea index >or=15 events per hour of sleep) was 68% and in the same range of all other individual components of MS. Moreover, OSA was associated with increased levels of glucose (P=.03) and glycosylated hemoglobin (P=.03) but not with body mass index (P=.30). Glycosylated hemoglobin was independently associated with glucose (P<.001) and apnea-hypopnea index (P=.03). The prevalence of OSA is in the same range as all the individual components of MS and is independently associated with impaired glycemic control.
Luciano F Drager; Eduardo L Queiroz; Heno F Lopes; Pedro R Genta; Eduardo M Krieger; Geraldo Lorenzi-Filho
Related Documents :
11106205 - Nasal obstruction as a risk factor for sleep apnoea syndrome.
15672855 - Gender difference in sleep profile of severely obese patients with obstructive sleep ap...
21029995 - Pain tolerance and obstructive sleep apnea in the elderly.
22686135 - The association between anxiety and the degree of illness in mild obstructive sleep apn...
1348925 - Glucose attenuation of paradoxical sleep deficits in old rats.
20422065 - The epworth sleepiness scale: self-administration versus administration by the physicia...
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of the cardiometabolic syndrome     Volume:  4     ISSN:  1559-4572     ISO Abbreviation:  -     Publication Date:  2009  
Date Detail:
Created Date:  2009-07-20     Completed Date:  2009-09-24     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101284690     Medline TA:  J Cardiometab Syndr     Country:  United States    
Other Details:
Languages:  eng     Pagination:  89-95     Citation Subset:  IM    
Hypertension Unit, University of São Paulo Medical School, São Paulo, Brazil.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Biological Markers / blood
Blood Glucose / metabolism
Body Mass Index
Cross-Sectional Studies
Hemoglobin A, Glycosylated / metabolism
Hyperglycemia / blood,  epidemiology*,  physiopathology
Metabolic Syndrome X / blood,  epidemiology*,  physiopathology
Middle Aged
Severity of Illness Index
Sleep Apnea, Obstructive / blood,  epidemiology*,  physiopathology
Reg. No./Substance:
0/Biological Markers; 0/Blood Glucose; 0/Hemoglobin A, Glycosylated; 0/hemoglobin A1c protein, human

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Left ventricular structural and functional changes in the metabolic syndrome.
Next Document:  Utility of aspirin therapy in patients with the cardiometabolic syndrome and diabetes.