Document Detail


Obstructed uteri with a cervix and vagina.
MedLine Citation:
PMID:  20643405     Owner:  NLM     Status:  In-Process    
Abstract/OtherAbstract:
OBJECTIVE: To describe a rare anomaly of the female reproductive tract and review the embryology associated with the defect.
DESIGN: Case report and review of the literature.
SETTING: Major academic medical center.
PATIENT(S): A 14-year-old girl with two hemiuteri lacking any communication with a single normal midline cervix and vagina.
INTERVENTION(S): Diagnostic laparoscopy with chromopertubation to identify the anomaly and subsequent bilateral supracervical hemihysterectomies.
MAIN OUTCOME MEASURE(S): Incidence, pathogenesis, fertility implications, and treatment options for patients with congenital defects in the upper vagina, cervix, and uterus.
RESULT(S): Based on classic embryology, the lower vagina forms from the urogenital sinus while the upper vagina, cervix, and uterus form from the müllerian ducts. If a cervix is present, then the upper vagina and uterus are also usually present and should communicate.
CONCLUSION(S): This anomaly cannot be fully explained by traditional embryologic developmental theory. It is likely that an insult occurred between 9 weeks, when the uterovaginal canal is formed, and 12 weeks, when the müllerian ducts fuse.
Authors:
Kelly Nicole Wright; Ogochukwu Okpala; Marc R Laufer
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Fertility and sterility     Volume:  95     ISSN:  1556-5653     ISO Abbreviation:  Fertil. Steril.     Publication Date:  2011 Jan 
Date Detail:
Created Date:  2010-12-20     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0372772     Medline TA:  Fertil Steril     Country:  United States    
Other Details:
Languages:  eng     Pagination:  290.e17-9     Citation Subset:  IM    
Copyright Information:
Copyright © 2011 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.
Affiliation:
Division of Gynecology, Children's Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA.
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