Document Detail

Obstetric outcomes of women with intracranial neoplasms.
MedLine Citation:
PMID:  19155008     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To determine the obstetric outcomes of women diagnosed with a primary intracranial neoplasm prior to or during pregnancy and the puerperium. METHODS: Demographic data, neurologic, obstetric, and neonatal outcomes were extracted retrospectively from charts identified from two hospital databases. RESULTS: Twenty-two patients with 25 pregnancies were identified. Thirteen patients were diagnosed prior to pregnancy (group 1); tumor growth or recurrence during pregnancy occurred in 3 patients. Nine patients were diagnosed during pregnancy and the puerperium (group 2); 7 underwent neurosurgery at a mean gestational age of 27+/-5.7 weeks; 2 experienced permanent visual loss. Significantly more gliomas occurred in group 1, but there were significantly more meningiomas in group 2. Numbers of cesarean delivery, preterm delivery at less than 34 weeks, and NICU admission were higher in group 2 than group 1, but this was not statistically significant. CONCLUSION: Although not statistically significant, neurologic deterioration during pregnancy may be associated with cesarean delivery, preterm delivery, and NICU admission.
Nadine Johnson; Mathew Sermer; Andrea Lausman; Cynthia Maxwell
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Publication Detail:
Type:  Journal Article     Date:  2009-01-19
Journal Detail:
Title:  International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics     Volume:  105     ISSN:  1879-3479     ISO Abbreviation:  Int J Gynaecol Obstet     Publication Date:  2009 Apr 
Date Detail:
Created Date:  2009-03-24     Completed Date:  2009-06-12     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0210174     Medline TA:  Int J Gynaecol Obstet     Country:  Ireland    
Other Details:
Languages:  eng     Pagination:  56-9     Citation Subset:  IM    
Division of Maternal-Fetal Medicine, Mount Sinai Hospital, Department of Obstetrics and Gynecology, University of Toronto, Toronto, Canada.
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MeSH Terms
Brain Neoplasms / complications*,  physiopathology,  surgery
Cesarean Section / statistics & numerical data
Databases, Factual
Glioma / complications,  physiopathology,  surgery
Infant, Newborn
Intensive Care Units, Neonatal / statistics & numerical data
Meningioma / complications,  physiopathology,  surgery
Neoplasm Recurrence, Local / epidemiology
Ontario / epidemiology
Postpartum Period
Pregnancy Complications, Neoplastic / physiopathology*
Pregnancy Outcome*
Premature Birth / etiology
Retrospective Studies
Vision Disorders / epidemiology,  etiology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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