| Obstetric outcome of women with uterine anomalies in China. | |
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MedLine Citation:
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PMID: 20193480 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Congenital uterine anomalies are associated with the highest incidence of reproductive failure and obstetric complications. This study aimed to summarize the clinical characteristics and prenatal outcome of pregnancy in women with congenital uterine malformations. METHODS: This retrospective study evaluated the fertility and obstetric outcome of 116 inpatients with uterine malformations with pregnancy in Peking University Third Hospital from June 1998 to June 2009. A total of 270 randomly selected pregnant women with a previously confirmed normally shaped uterus as a control group. Student's t test and analysis of variance (ANOVA) were used to compare means for normally distributed variables. The analysis was carried out using the SPSS. RESULTS: Among 21 961 deliveries in Peking University Third Hospital, 116 (0.45%) were in women with uterine anomalies. A septate uterus was present in 43 (37.1%) and the uterus didelphys in 28 (24.2%) of the 116 women identified. Bicornuate uterus, arcuate and unicomate uterus were observed in 12 (10.3%), 18 (15.5%) and 15 (12.9%) patients, respectively. Patients with uterine anomalies had significantly higher rates of malpresentation (38.8%), preterm delivery (19.8%), and cesarean section (78.5%) compared with the group of women with a normal uterus. Patients with uterine anomalies had significantly lower mean birth-weight neonates and a significantly higher incidence of small for gestationalage (SGA) neonates; women with uterus didelphys more frequently required infertility treatment than patients with other uterine anomalies (P < 0.001). The rate of malpresentation was significantly higher in patients with septated uterus in comparison with patients with uterus unicorns (P < 0.05). CONCLUSIONS: Women with congenital uterinemal formation usually have higher incidence of complications during pregnancy and delivery. A septate uterus appears to be associated with poorer obstetric outcomes. |
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Authors:
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Yan Zhang; Yang-yu Zhao; Jie Qiao |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Chinese medical journal Volume: 123 ISSN: 0366-6999 ISO Abbreviation: Chin. Med. J. Publication Date: 2010 Feb |
Date Detail:
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Created Date: 2010-03-02 Completed Date: 2010-05-27 Revised Date: 2010-09-14 |
Medline Journal Info:
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Nlm Unique ID: 7513795 Medline TA: Chin Med J (Engl) Country: China |
Other Details:
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Languages: eng Pagination: 418-22 Citation Subset: IM |
Affiliation:
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Department of Obstetrics and Gynaecology, Peking University Third Hospital, Beijing 100083, China. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Birth Weight Cesarean Section China Female Humans Infant, Low Birth Weight Infant, Newborn Infertility, Female Obstetric Labor Complications / physiopathology Pregnancy Pregnancy Complications / physiopathology* Pregnancy Outcome Premature Birth Retrospective Studies Uterine Diseases / complications*, physiopathology* Young Adult |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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