Document Detail

Obstetric outcome in women with endometriosis--a matched case-control study.
MedLine Citation:
PMID:  14614250     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Immunological deficiencies, altered angiogenic activity, infiltrative potential and growth factors are plausible factors behind endometriosis. The aim of this study was to determine whether endometriosis interferes with the course or outcome of pregnancy. STUDY DESIGN: In this matched case-control study, we analyzed obstetric outcome among 137 women with endometriosis and 137 controls matched as regards IVF procedures and parity who gave singleton births at Kuopio University Hospital between January 1994 and December 2000. In affected women, the diagnosis was histologically verified, whereas the controls were eligible for the study only if they had undergone laparoscopy/tomy in connection with tubal sterilization, or infertility unrelated to endometriosis. RESULTS: No statistically significant differences were detected in reproductive risk factors in women with endometriosis, with the exception of mean maternal age (31.2 years in the cases vs. 34 years in the controls). The mean birth weight (+/-SD) among those delivering at term (>37 completed weeks) was 3,600 (+/-542) g in the control group and 3,547 (+/-456) g in the study group. Placental weight was comparable in both groups. Overall pregnancy characteristics and pregnancy outcome measures were similar in women affected by endometriosis when compared with the control group. CONCLUSIONS: Any potential negative effect of endometriosis on obstetric outcome was undetectable.
Minna Kortelahti; Maarit A Anttila; Maritta I Hippeläinen; Seppo T Heinonen
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2003-11-11
Journal Detail:
Title:  Gynecologic and obstetric investigation     Volume:  56     ISSN:  0378-7346     ISO Abbreviation:  Gynecol. Obstet. Invest.     Publication Date:  2003  
Date Detail:
Created Date:  2003-12-10     Completed Date:  2004-04-02     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7900587     Medline TA:  Gynecol Obstet Invest     Country:  Switzerland    
Other Details:
Languages:  eng     Pagination:  207-12     Citation Subset:  IM    
Copyright Information:
Copyright 2003 S. Karger AG, Basel
Department of Obstetrics and Gynecology, Kuopio University Hospital, Kuopio, Finland.
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MeSH Terms
Birth Weight
Case-Control Studies
Endometriosis / complications*
Fertilization in Vitro
Organ Size
Placenta / anatomy & histology
Pregnancy Complications*
Pregnancy Outcome*

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