Document Detail


Obstetric complications in histories of monozygotic twins discordant and concordant for schizophrenia.
MedLine Citation:
PMID:  8178679     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Histories of obstetric complications (OCs) during pregnancy, labor-delivery and the neonatal period were investigated by detailed maternal report for 23 monozygotic (MZ) twin pairs discordant for schizophrenia, 10 MZ twin pairs concordant for schizophrenia and 7 normal MZ control pairs. Statistically significant differences in OC rates were found across these 3 groups. OCs being most frequent in discordant pairs and least frequent in normal control pairs. Labor complications were significantly more frequent in discordant than concordant pairs. OC rates were equivalent in sick and well discordant twins. The results provide evidence for the role of OCs in the development of schizophrenia, complications at the time of birth being especially associated with the development of schizophrenia in discordant twins.
Authors:
T F McNeil; E Cantor-Graae; E F Torrey; K Sjöström; A Bowler; E Taylor; R Rawlings; E S Higgins
Related Documents :
10789269 - Greater occurrence of schizophrenia in dizygotic but not monozygotic twins. register-ba...
25358469 - Differentiation of genetic abnormalities in early pregnancy loss.
291279 - Taste acuity of the human palate. iii. studies with taste solutions on subjects in diff...
15959659 - Subtypes of autism by cluster analysis based on structural mri data.
25287809 - Fetal pulse oximetry for fetal assessment in labour.
16112739 - Schizotypy and mixed-handedness revisited.
23335029 - Perinatal outcome after selective feticide in monochorionic twin pregnancies.
18843529 - Initiation of and barriers to prenatal care use among low-income women in san antonio, ...
23791929 - Alobar holoprosencephaly with cyclopia-autopsy-based observations from one medical center.
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Acta psychiatrica Scandinavica     Volume:  89     ISSN:  0001-690X     ISO Abbreviation:  Acta Psychiatr Scand     Publication Date:  1994 Mar 
Date Detail:
Created Date:  1994-06-09     Completed Date:  1994-06-09     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  0370364     Medline TA:  Acta Psychiatr Scand     Country:  DENMARK    
Other Details:
Languages:  eng     Pagination:  196-204     Citation Subset:  IM    
Affiliation:
Department of Psychiatry, Lund University, Malmõ, Sweden.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adult
Birth Weight / genetics
Diseases in Twins / genetics*,  psychology
Female
Humans
Male
Middle Aged
Obstetric Labor Complications / etiology*,  psychology
Phenotype
Pregnancy
Risk Factors
Schizophrenia / diagnosis,  genetics*
Schizophrenic Psychology*
Social Environment
Twins, Monozygotic / genetics,  psychology
Grant Support
ID/Acronym/Agency:
NIMH MH41176/MH/NIMH NIH HHS

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Interrater reliability of the Structured Clinical Interview for the Positive and Negative Syndrome S...
Next Document:  Age and other factors relevant to the rehospitalization of schizophrenic outpatients.