| Obstetric complications in children born to parents with schizophrenia: a meta-analysis of case-control studies. | |
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MedLine Citation:
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PMID: 8685284 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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On the basis of previous findings, we used meta-analyses to consider whether births to parents with schizophrenia have an increased risk of obstetric complications. Meta-analyses were based on published studies satisfying the following selection criteria. The schizophrenic diagnosis could apply to either parent: parents with non-schizophrenic psychoses were not included: only normal controls were accepted. In all, 14 studies provided effect sizes or data from which these could be derived. Studies were identified by data searches through MEDLINE, PSYCLIT and through references of papers relating to the subject. Births to individuals with schizophrenia incur an increased risk of pregnancy and birth complications, low birthweight and poor neonatal condition. However, in each case the effect size is small (mean r = 0.155; 95% CI = 0.057). The risk is greater for mothers with schizophrenia and is not confined to mothers with onset pre-delivery or to the births of the children who become schizophrenic themselves. |
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Authors:
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A Sacker; D J Done; T J Crow |
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Publication Detail:
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Type: Journal Article; Meta-Analysis; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Psychological medicine Volume: 26 ISSN: 0033-2917 ISO Abbreviation: Psychol Med Publication Date: 1996 Mar |
Date Detail:
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Created Date: 1996-08-19 Completed Date: 1996-08-19 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 1254142 Medline TA: Psychol Med Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 279-87 Citation Subset: IM |
Affiliation:
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Department of Psychiatry, University of Oxford. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Brain Damage, Chronic / diagnosis*, psychology Child of Impaired Parents / psychology* Delirium, Dementia, Amnestic, Cognitive Disorders / diagnosis*, genetics, psychology Female Humans Infant, Newborn Obstetric Labor Complications / diagnosis*, psychology Pregnancy Pregnancy Outcome Risk Factors Schizophrenia / diagnosis*, genetics Schizophrenic Psychology* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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