Document Detail

Obsessionality, obsessive-compulsive disorder, and temporal lobe epilepsy.
MedLine Citation:
PMID:  16150651     Owner:  NLM     Status:  MEDLINE    
We evaluated the prevalence of obsessive-compulsive disorder (OCD) in patients with temporal lobe epilepsy (TLE) and we investigated the hypothesis that obsessionality may represent a trait in TLE. Eighty-two consecutive patients with epilepsy, 62 with TLE and 20 with idiopathic generalized epilepsy (IGE), and 82 matched healthy controls were evaluated using the SCID-IP, Y-BOCS, MMPI-2 (specifically the Psychasthenia and Obsessiveness scales), BDI, and STAI Y1 and Y2. Nine of the TLE patients, none of the IGE patients, and one of the controls had a diagnosis of OCD. Psychasthenia and Obsessiveness scores were significantly higher in the TLE than in the IGE and control groups. Patients with TLE and OCD differed significantly with respect to history of depression when compared with patients with TLE without OCD, whereas there were no differences in age at onset and duration of epilepsy, seizure pattern and frequency, MRI features, laterality of the EEG focus, antiepileptic drug therapy and combinations, and BDI scores.
Francesco Monaco; Andrea Cavanna; Elena Magli; Davide Barbagli; Laura Collimedaglia; Roberto Cantello; Marco Mula
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2005-09-16
Journal Detail:
Title:  Epilepsy & behavior : E&B     Volume:  7     ISSN:  1525-5050     ISO Abbreviation:  Epilepsy Behav     Publication Date:  2005 Nov 
Date Detail:
Created Date:  2005-10-28     Completed Date:  2005-12-20     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  100892858     Medline TA:  Epilepsy Behav     Country:  United States    
Other Details:
Languages:  eng     Pagination:  491-6     Citation Subset:  IM    
Neuropsychiatry Research Group and the Epilepsy Clinic, Department of Neurology, Amedeo Avogadro University, Novara, Italy.
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MeSH Terms
Anticonvulsants / therapeutic use
Epilepsy, Generalized / complications,  physiopathology
Epilepsy, Temporal Lobe / complications,  psychology*
Magnetic Resonance Imaging
Middle Aged
Neuropsychological Tests
Obsessive Behavior / complications,  psychology*
Obsessive-Compulsive Disorder / complications,  psychology*
Psychiatric Status Rating Scales
Reg. No./Substance:

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