Document Detail

Observations on variability of atrioventricular nodal conduction in man and the dual-pathway response.
MedLine Citation:
PMID:  3229439     Owner:  NLM     Status:  MEDLINE    
A study was made of nodal conduction times of atrial stimuli with fixed coupling intervals, in 23 patients divided into two groups according to their atrial stimulus test response: Group I (continuous AV node function curve; 17 cases) and Group II (dual AV node pathway; six cases). The stimulation protocol involved the delivery of 75 stimuli with a fixed coupling interval 20 ms greater than the effective refractory period (ERP) of the AV node (Group I) or fast pathway (Group II). The atrial coupling intervals (A1A2) and node conduction times (A2H2) were measured. An evaluation was made of the dispersion of intervals with range (R) and of the distribution of A2H2 times (X2 test). In both Groups, R (A2H2) was greater than R(A1A2) (P less than 0.05); R(A2H2) in Group II was greater than R(A2H2) in Group I (P less than 0.001). In Group I the distribution of A2H2 was non-normal in four cases and bimodal in five; in Group II the distribution was non-normal and bimodal in all cases. It is concluded that: (1) the AV node generates a dispersion in its conduction times in the vicinity of its ERP, although the nodal conduction curve is continuous; and (2) the so-called dual pathway may constitute an exaggeration of AV node response inhomogeneity.
J Sanchis; V López-Merino; R Sanjuán; S Morell; F J Chorro; R García-Civera; A Llácer
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  European heart journal     Volume:  9     ISSN:  0195-668X     ISO Abbreviation:  Eur. Heart J.     Publication Date:  1988 Sep 
Date Detail:
Created Date:  1989-04-17     Completed Date:  1989-04-17     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  8006263     Medline TA:  Eur Heart J     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  991-6     Citation Subset:  IM    
Cardiology Service and Coronary Care Unit, Valencia University Clinic Hospital, Spain.
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MeSH Terms
Arrhythmias, Cardiac / physiopathology*
Atrioventricular Node / physiopathology*
Bundle of His / physiopathology
Cardiac Pacing, Artificial
Heart Conduction System / physiopathology*
Middle Aged
Tachycardia, Atrioventricular Nodal Reentry / physiopathology

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