Document Detail

Observations on the surface area of the abnormal transformation zone associated with intraepithelial and early invasive squamous cell lesions of the cervix.
MedLine Citation:
PMID:  562069     Owner:  NLM     Status:  MEDLINE    
The apparent area of the abnormal transformation zone (TZ) of the cervix was measured in a total of 104 patients by a simple method with the use of the 1 and 5 mm. diameter circle in the center of the field of the Leisegang colposcope and the field of the colposcope itself. The visible area (mean +/- S.E.M.) of the abnormal TZ for five patients with microinvasive or occult carcinoma of the cervix (180.8 mm.2 +/- 62.2) was significantly larger (p less than 0.01) than that of 64 patients with major intraepithelial lesions (62.5 sq. mm.2 +/- 7.3) and 35 patients with minor intraepithelial lesions (45.8 sq. mm.2 +/- 11.7). The visible area of the abnormal TZ measured over 40 mm.2 in each of the five patients with invasive lesions but in only 42 of 99 (42%) patients with intraepithelial lesions. The TZ extended into the endocervical canal and could not be fully visualized in four (80%) of the patients with invasive lesions, 24 (38%) of patients with major intraepithelial lesions, and 11 (31%) of patients with minor intraepithelial lesions. The implications of these findings are discussed.
R M Rome; R Urcuyo; J H Nelson
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  American journal of obstetrics and gynecology     Volume:  129     ISSN:  0002-9378     ISO Abbreviation:  Am. J. Obstet. Gynecol.     Publication Date:  1977 Nov 
Date Detail:
Created Date:  1977-11-30     Completed Date:  1977-11-30     Revised Date:  2005-11-17    
Medline Journal Info:
Nlm Unique ID:  0370476     Medline TA:  Am J Obstet Gynecol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  565-70     Citation Subset:  AIM; IM    
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MeSH Terms
Age Factors
Carcinoma / complications,  pathology*
Carcinoma, Squamous Cell / complications,  pathology*
Cell Transformation, Neoplastic / pathology*
Middle Aged
Pregnancy Complications
Uterine Cervical Dysplasia / pathology
Uterine Cervical Neoplasms / complications,  pathology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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